Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349862 | 0.83 | MEN1 (0.43) | MEN1KMT2AMAPTHSD11B1ACLY | |
| SCHEMBL10349699 | 0.80 | MEN1 (0.52) | MEN1KMT2AMAPTHSD11B1ACLY | |
| SCHEMBL10634947 | 0.78 | HSD11B1 (0.45) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL23780405 | 0.77 | MEN1 (0.49) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL13420339 | 0.74 | HSD11B1 (0.53) | MEN1KMT2AHSD11B1ACLYACACA | |
| SCHEMBL10049047 | 0.72 | KMT2A (0.67) | MEN1KMT2AMAPTHSD11B1ACLY | |
| SCHEMBL13420513 | 0.72 | HSD11B1 (0.54) | MEN1KMT2AMAPTHSD11B1ACLY | |
| SCHEMBL14046876 | 0.72 | HSD11B1 (0.54) | MEN1KMT2AMAPTHSD11B1ACLY | |
| SCHEMBL13420642 | 0.72 | HSD11B1 (0.54) | MEN1KMT2AMAPTHSD11B1ACLY | |
| SCHEMBL13420201 | 0.72 | HSD11B1 (0.54) | MEN1KMT2AMAPTHSD11B1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166542-B1 | TRITERPENYL ESTERS OF ORGANIC ACIDS, PROCESS FOR THEIR PRODUCTION, AND HYPOLIPIDEMIC AGENTS COMPOSED OF THEM | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1990-08-08 | — | — | EP | claimed |