Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10350854 | 1.00 | KMT2A (0.44) | KMT2AMEN1ALDH1A1TSHRNR1I2 | |
| SCHEMBL5321423 | 0.80 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1TSHRNR1I2 | |
| SCHEMBL27602419 | 0.80 | MEN1 (0.44) | KMT2AMEN1ALDH1A1TSHRNR1I2 | |
| SCHEMBL10349965 | 0.77 | SMN1; SMN2 (0.39) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL10349963 | 0.77 | SMN1; SMN2 (0.39) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL10592490 | 0.77 | MEN1 (0.61) | KMT2AMEN1ALDH1A1TSHRNR1I2 | |
| SCHEMBL10592487 | 0.77 | MEN1 (0.61) | KMT2AMEN1ALDH1A1TSHRNR1I2 | |
| SCHEMBL61899 | 0.75 | MEN1 (0.48) | KMT2AMEN1ALDH1A1NR1I2LMNA | |
| Benzaldehyde SCHEMBL367504 | 0.75 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1NR1I2LMNA | |
| Benzaldehyde SCHEMBL4954589 | 0.73 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1TSHRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201221-B1 | 6-(1-ACYL-1-HYDROXY METHYL) PENICILLANIC ACID DERIVATIVES | PFIZER INC. (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4762921-A | 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives | PFIZER INC. (US) | 1988-08-09 | — | — | US | disclosed |
| US-4675186-A | 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives | PFIZER INC. (US) | 1987-06-23 | — | — | US | disclosed |
| EP-0201221-A1 | 6-(1-acyl-1-hydroxy methyl) penicillanic acid derivatives | PFIZER INC. (US) | 1986-11-12 | — | — | EP | disclosed |