SCHEMBL61899

SCHEMBL61899

CCOC(C)OC(=O)C(=Cc1ccccc1)OC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
ABCG2 Q9UNQ0 1/20 0.41
NR1I2 O75469 1/20 0.39
RECQL P46063 1/20 0.38
POLB P06746 2/20 0.38
NR1H4 Q96RI1 1/20 0.38
ALDH1A1 P00352 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 3/20 0.36
MAPT P10636 3/20 0.36
PLIN1 O60240 1/20 0.36
PLIN5 Q00G26 1/20 0.36
ABHD5 Q8WTS1 1/20 0.36
EGFR P00533 1/20 0.36
AKR1C3 P42330 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
NPSR1 Q6W5P4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15837 0.82 GAA (0.47) MEN1KMT2AABCG2RECQLALDH1A1
SCHEMBL19579512 0.80 ALDH1A1 (0.51) MEN1KMT2AALDH1A1LMNA
SCHEMBL15189 0.79 MEN1 (0.70) MEN1KMT2AABCG2NR1I2POLB
SCHEMBL9972668 0.79 MEN1 (0.70) MEN1KMT2AABCG2NR1I2POLB
SCHEMBL28732347 0.77 ABCG2 (0.53) MEN1KMT2AABCG2RECQLALDH1A1
SCHEMBL1397476 0.77 ABCG2 (0.53) MEN1KMT2AABCG2RECQLALDH1A1
SCHEMBL28972205 0.76 CTSK (0.42) MEN1KMT2AABCG2RECQLPOLB
SCHEMBL27602419 0.76 MEN1 (0.44) MEN1KMT2ANR1I2RECQLPOLB
SCHEMBL10350855 0.75 KMT2A (0.44) MEN1KMT2ANR1I2POLBNR1H4
SCHEMBL10350854 0.75 KMT2A (0.44) MEN1KMT2ANR1I2POLBNR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10555892-B1 Functionalized siloxane or polysiloxane coated particles with enhanced light filtering properties NANOPHASE TECHNOLOGIES CORPORATION (US) 2020-02-11 US claimed
US-20150174045-A1 LIGHT PROTECTING COMPOSITION WITH REDUCED TOTAL AMOUNT OF UV FILTER CONTAINING A POLYSILOXANE-BASED UV FILTER DSM IP ASSETS B.V. (NL) 2015-06-25 US claimed
WO-2013102248-A2 \"AQUEOUS COSMETIC SUNSCREEN COMPOSITION AND USE THEREOF, COSMETIC METHOD FOR APPLICATION OF SAID COMPOSITION, COSMETIC METHOD TO PREVENT AND CONTROL SKIN OILINESS, COSMETIC METHOD TO PROTECT THE SKIN FROM THE DAMAGES CAUSED BY ULTRAVIOLET RADIATION, AND COSMETIC PRODUCT.\ . JOHNSON & JOHNSON DO BRASIL INDUSTRIA E COMERCIO DE PRODUTOS PARA SAUDE LTDA. (BR) 2013-07-11 WO claimed
EP-1899015-B1 COMPOSITION WITH TIGHT CAPSULES CONTAINING A SUNSCREEN AGENT DSM IP ASSETS BV (NL) 2012-03-21 EP claimed
WO-2009129855-A1 PHOTOPROTECTIVE COMPOSITIONS CONTAINING PEPTIDES UNITED TECHNOLOGIES UT AG (CH) 2009-10-29 WO claimed
US-20080199526-A1 Composition With Tight Capsules Containing a Sunscreen Agent DSM IP ASSETS B.V. (NL) 2008-08-21 US claimed
EP-1899015-A1 COMPOSITION WITH TIGHT CAPSULES CONTAINING A SUNSCREEN AGENT DSMIP Assets B.V. (NL) 2008-03-19 EP claimed
WO-2007000316-A1 COMPOSITION WITH TIGHT CAPSULES CONTAINING A SUNSCREEN AGENT DSM IP ASSETS B.V. (NL) 2007-01-04 WO claimed
WO-2026087156-A1 PERSONAL CARE COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2026-04-30 WO disclosed
US-12582587-B2 Sunscreen composition and methods of protection from ultraviolet and visible light DOC MARTIN'S OF MAUI (US) 2026-03-24 US disclosed
EP-4665297-A1 A COSMETIC COMPOSITION Unilever IP Holdings B.V. (NL) 2025-12-24 EP disclosed
US-12409115-B2 Sunscreen composition comprising visible light protecting agents and methods of use DOC MARTIN'S OF MAUI (US) 2025-09-09 US disclosed
EP-3471694-B1 SUNSCREEN COMPOSITIONS CONTAINING A COMBINATION OF A LINEAR ULTRAVIOLET RADIATION-ABSORBING POLYETHER AND OTHER ULTRAVIOLET-SCREENING COMPOUNDS KENVUE BRANDS LLC (US) 2025-07-02 EP disclosed
CN-120201986-A Sun-proof cosmetic 株式会社高丝 2025-06-24 CN disclosed
EP-0998906-A2 Shampoo composition F. HOFFMANN-LA ROCHE AG (CH) 2000-05-10 EP disclosed
EP-0979645-A1 Light screening composition containing a polysiloxane type UV-B screening agent and a benzimidazol type UV-B screening agent F. HOFFMANN-LA ROCHE AG (CH) 2000-02-16 EP disclosed
US-6018044-A TRIS((ALKYL, SILANE, OLIGOSILOXANE OR POLYSILOXANE)(OXY OR AMINO)CARBONYL-(1,4-PHENYLENE)-AMINO)-S-TRIAZINES HAVING AT LEAST ONE SILICON CONTAINING MOIETY OF GIVEN FORMULA; USE AS UV-B FILTERS IN LIGHT SCREENING COMPOSITIONS ROCHE VITAMINS INC. (US) 2000-01-25 US disclosed
US-5985251-A DIBENZOYLMETHANE DERIVATIVE, 3,3-DIPHENYLACRYLATE- OR BENZYLIDENE CAMPHOR DERIVATIVE, P-METHOXYCINNAMATE DERIVATIVE, ROCHE VITAMINS INC. (US) 1999-11-16 US disclosed
EP-0933376-A2 Silanyl-triazines as light screening compositions F. HOFFMANN-LA ROCHE AG (CH) 1999-08-04 EP disclosed
EP-0920858-A2 Light screening composition F. HOFFMANN-LA ROCHE AG (CH) 1999-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10555892-B1 Functionalized siloxane or polysiloxane coated particles with enhanced light filtering properties SPIN4, RPS4X, RPS4Y1 MEN1 4144/4885KMT2A 2398/4885ABCG2 1411/4885
US-12582587-B2 Sunscreen composition and methods of protection from ultraviolet and visible light SOD1, TYR, SLC40A1 MEN1 2954/4885KMT2A 3242/4885ABCG2 692/4885
US-20080199526-A1 Composition With Tight Capsules Containing a Sunscreen Agent SUN2, DSG1, DSC1 MEN1 1001/4885KMT2A 3066/4885ABCG2 42/4885
US-20150174045-A1 LIGHT PROTECTING COMPOSITION WITH REDUCED TOTAL AMOUNT OF UV FILTER CONTAINING A POLYSILOXANE-BASED UV FILTER ERCC4, ERCC2, ERCC1 MEN1 2569/4885KMT2A 2377/4885ABCG2 1698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.