Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | MDM4 | O15151 | 2/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28024836 | 0.86 | CETP (0.53) | CETPTP53MDM4MDM2KMT2A | |
| SCHEMBL10351503 | 0.85 | CETP (0.41) | CETPTP53MDM4MDM2KMT2A | |
| SCHEMBL11364195 | 0.85 | CETP (0.49) | CETPTP53MDM4MDM2KMT2A | |
| SCHEMBL2935482 | 0.81 | KMT2A (0.68) | TP53KMT2AMEN1L3MBTL1TDP1 | |
| SCHEMBL13846423 | 0.78 | MAPT (0.51) | CETPTP53MDM4MDM2KMT2A | |
| SCHEMBL30513842 | 0.77 | CETP (0.44) | CETPTP53MDM4MDM2KMT2A | |
| SCHEMBL3690292 | 0.76 | TDP1 (0.50) | CETPTP53MDM4MDM2KMT2A | |
| SCHEMBL16204250 | 0.75 | ADRA2C (0.44) | CETPTP53MDM4MDM2L3MBTL1 | |
| SCHEMBL11518250 | 0.75 | ITGB3 (0.50) | CETPTP53MDM4MDM2KMT2A | |
| SCHEMBL4654049 | 0.74 | TDP1 (0.72) | KMT2AMEN1L3MBTL1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128891-B1 | DEODORIZED COMPOSITIONS | MONSANTO COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4770806-A | ACTIVATED CARBON AND ORGANIC SULFUR COMPOUND RUBBER ADDITIVE | MONSANTO COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0128891-A2 | Deodorized compositions | MONSANTO COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |
| EP-0008177-B1 | VULCANIZABLE RUBBER COMPOSITIONS CONTAINING SUBSTITUTED CARBAMIC ACID ESTERS | MONSANTO COMPANY (US) | 1981-08-26 | — | — | EP | disclosed |
| EP-0008177-A1 | Vulcanizable rubber compositions containing substituted carbamic acid esters | MONSANTO COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4156680-A | Scorch inhibited vulcanizable rubber compositions containing carbamic acid esters | MONSANTO COMPANY (US) | 1979-05-29 | — | — | US | disclosed |