Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351881 | 0.83 | RAB9A (0.48) | RAB9ATDP1POLBKDM4EMEN1 | |
| SCHEMBL11130014 | 0.79 | RAB9A (0.48) | RAB9ATDP1POLBKDM4EMEN1 | |
| SCHEMBL28185888 | 0.79 | RAB9A (0.48) | RAB9ATDP1POLBKDM4EMEN1 | |
| SCHEMBL9277949 | 0.79 | RAB9A (0.51) | RAB9ATDP1POLBKDM4EMEN1 | |
| SCHEMBL24791572 | 0.79 | RAB9A (0.48) | RAB9ATDP1POLBKDM4EMEN1 | |
| SCHEMBL8505917 | 0.77 | TDP1 (0.48) | RAB9ATDP1POLBKDM4EMEN1 | |
| SCHEMBL7234935 | 0.77 | HTT (0.50) | RAB9ATDP1POLBKDM4EMEN1 | |
| SCHEMBL11216543 | 0.76 | RAB9A (0.43) | RAB9ATDP1POLBKDM4EMEN1 | |
| SCHEMBL10873957 | 0.76 | HTR6 (0.46) | RAB9ATDP1POLBKDM4EMEN1 | |
| SCHEMBL6112522 | 0.76 | RAB9A (0.54) | RAB9ATDP1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094821-B1 | PROCESS FOR THE NUCLEOPHILIC SUBSTITUTION OF UNACTIVATED AROMATIC AND HETEROAROMATIC SUBSTRATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-08 | — | — | EP | disclosed |
| US-4783285-A | CATALYZED BY ACYCLIC OR CYCLIC POLYETHER | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1988-11-08 | — | — | US | disclosed |
| US-4683091-A | Process for the nucleophilic substitution of unactivated aromatic and heteroaromatic substrates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| EP-0094821-A1 | Process for the nucleophilic substitution of unactivated aromatic and heteroaromatic substrates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-11-23 | — | — | EP | disclosed |