Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | ACHE | P22303 | 5/20 | 0.49 |
| ▸ | BCHE | P06276 | 4/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351216 | 0.90 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL8870944 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL10350723 | 0.79 | ALDH1A1 (0.70) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL10848027 | 0.78 | ACHE (0.66) | ALDH1A1KDM4EACHEBCHEGRIN1 | |
| SCHEMBL10351232 | 0.78 | KDM4E (0.68) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL10351811 | 0.76 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL10350749 | 0.75 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL10351438 | 0.75 | ACHE (0.64) | ACHEBCHEGRIN1GRIN2ARAD52 | |
| SCHEMBL10350717 | 0.74 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL10350724 | 0.74 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371388-A2 | Acridine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |