SCHEMBL10352175

SCHEMBL10352175

CCOCCOc1ccc(N)c(C(F)(F)F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 9/20 0.50
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
KMT2A Q03164 1/20 0.41
APOBEC3G Q9HC16 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
ATM Q13315 1/20 0.40
FFAR4 Q5NUL3 3/20 0.39
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
P2RY12 Q9H244 1/20 0.38
THRA P10827 2/20 0.38
THRB P10828 1/20 0.38
KDM4E B2RXH2 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CASP1 P29466 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10352007 0.86 MAPT (0.48) MEN1NPC1KMT2AAPOBEC3GL3MBTL1
SCHEMBL10269779 0.86 THRA (0.48) MEN1NPC1KMT2AAPOBEC3GL3MBTL1
SCHEMBL4230857 0.85 KMT2A (0.54) MEN1NPC1KMT2AAPOBEC3GL3MBTL1
SCHEMBL10352711 0.84 FFAR4 (0.43) MEN1NPC1KMT2AAPOBEC3GL3MBTL1
Hydrochloric Acid SCHEMBL185985 0.84 KMT2A (0.53) MEN1NPC1KMT2AAPOBEC3GL3MBTL1
SCHEMBL10352006 0.83 THRA (0.52) NPC1LMNAMAPTTHRATHRB
SCHEMBL10352595 0.82 THRA (0.54) NPC1LMNAMAPTTHRATHRB
SCHEMBL10352177 0.82 THRA (0.54) NPC1LMNAMAPTTHRATHRB
SCHEMBL10352020 0.82 THRA (0.54) NPC1LMNAMAPTTHRATHRB
Dimethylamine SCHEMBL6718739 0.81 KMT2A (0.50) MEN1NPC1KMT2AAPOBEC3GL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300390-B1 TRIFLUOROMETHYL-ALKOXY-ANILIN, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE ICE-COLOUR TECHNIQUE HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-29 EP disclosed