Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | HTR1D | P28221 | 5/20 | 0.41 |
| ▸ | HTR1B | P28222 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10352177 | 1.00 | THRA (0.54) | THRATHRBTSHRNR5A1PDK2 | |
| SCHEMBL10352595 | 1.00 | THRA (0.54) | THRATHRBTSHRNR5A1PDK2 | |
| SCHEMBL10352006 | 0.98 | THRA (0.52) | THRATHRBTSHRNR5A1PDK2 | |
| SCHEMBL10269779 | 0.95 | THRA (0.48) | THRATHRBTSHRPDK2MAPT | |
| SCHEMBL10352007 | 0.89 | MAPT (0.48) | THRATHRBTSHRPDK2TP53 | |
| SCHEMBL31540270 | 0.83 | THRA (0.55) | THRATHRBTSHRNR5A1PDK2 | |
| SCHEMBL4230857 | 0.82 | KMT2A (0.54) | TSHRPDK2TP53MAPTNPC1 | |
| SCHEMBL25797626 | 0.82 | THRA (0.57) | THRATHRBTSHRNR5A1PDK2 | |
| SCHEMBL10352175 | 0.82 | NCF1 (0.50) | THRATHRBMAPTNPC1LMNA | |
| SCHEMBL10352711 | 0.81 | FFAR4 (0.43) | THRATHRBMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300390-B1 | TRIFLUOROMETHYL-ALKOXY-ANILIN, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE ICE-COLOUR TECHNIQUE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0300390-A1 | Trifluoromethyl-alkoxy-anilin, process for their preparation and their use in the ice-colour technique | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-25 | — | — | EP | disclosed |