SCHEMBL103525

SCHEMBL103525

C=Cc1ccc(OCOc2ccc(OC(=O)c3ccc(C=C)cc3)cc2-c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 1/20 0.40
KMT2A Q03164 4/20 0.39
MAPT P10636 3/20 0.39
MEN1 O00255 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
RAB9A P51151 1/20 0.39
PTGDR2 Q9Y5Y4 6/20 0.38
SYK P43405 1/20 0.37
AURKB Q96GD4 1/20 0.37
INCENP Q9NQS7 1/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
CYP3A4 P08684 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
EGFR P00533 1/20 0.37
PARP10 Q53GL7 1/20 0.36
PDGFRB P09619 1/20 0.36
PDGFRA P16234 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16812835 0.88 KMT2A (0.44) CA9KMT2AMAPTMEN1TDP1
SCHEMBL103307 0.81 HPGD (0.36) KMT2AMAPTMEN1TDP1RAB9A
SCHEMBL102853 0.81 TDP1 (0.39) KMT2AMAPTTDP1L3MBTL1GAA
SCHEMBL13310810 0.81 MAPT (0.39) KMT2AMAPTMEN1RAB9ACYP3A4
SCHEMBL103294 0.80 KMT2A (0.47) KMT2AMAPTRAB9APRSS1PRSS2
SCHEMBL13310808 0.80 KMT2A (0.47) KMT2AMAPTRAB9APRSS1PRSS2
SCHEMBL13032731 0.80 KMT2A (0.48) CA9KMT2AMAPTMEN1TDP1
SCHEMBL13774490 0.77 KMT2A (0.42) KMT2AMAPTMEN1TDP1RAB9A
SCHEMBL13390123 0.76 NPC1 (0.38) KMT2AMAPTMEN1TDP1RAB9A
SCHEMBL17897412 0.76 PTGDR2 (0.35) KMT2AMAPTMEN1PTGDR2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011773-B2 Liquid crystal display device DIC CORPORATION (JP) 2018-07-03 US disclosed
US-9809752-B2 Liquid crystal display device DIC CORPORATION (JP) 2017-11-07 US disclosed
US-20160215217-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-07-28 US disclosed
US-20160130502-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-05-12 US disclosed
US-8992796-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2015-03-31 US disclosed
US-20140327862-A1 FERROELECTRIC LIQUID CRYSTAL COMPOSITION AND FERROELECTRIC LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2014-11-06 US disclosed
US-20140313468-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2014-10-23 US disclosed
US-8405799-B2 Polymer-stabilized liquid crystal composition, liquid crystal display device, method for producing liquid crystal display device DIC CORPORATION (JP) 2013-03-26 US disclosed
US-20120056129-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2012-03-08 US disclosed
US-7871540-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2011-01-18 US disclosed
US-20100149446-A1 POLYMER-STABILIZED LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE, METHOD FOR PRODUCING LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2010-06-17 US disclosed
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2009-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION H1-0, H1-4, H1-10 CA9 1698/4885KMT2A 1510/4885MAPT 1343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.