Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11032767 | 0.86 | KDM4E (0.66) | CYP1A2CYP2D6KDM4ELMNACHRM2 | |
| Flavoxate SCHEMBL29421720 | 0.76 | LMNA (1.00) | CYP1A2CYP2D6KDM4ELMNACHRM2 | |
| Flavoxate SCHEMBL25801 | 0.76 | LMNA (1.00) | CYP1A2CYP2D6KDM4ELMNACHRM2 | |
| SCHEMBL10841490 | 0.75 | CYSLTR1 (0.59) | CYP1A2CYP2D6KDM4ECYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL10549683 | 0.75 | LMNA (0.85) | CYP1A2CYP2D6KDM4ELMNACHRM2 | |
| Flavoxate SCHEMBL124540 | 0.75 | LMNA (0.98) | CYP1A2CYP2D6KDM4ELMNACHRM2 | |
| Flavoxate SCHEMBL29395220 | 0.75 | LMNA (0.98) | CYP1A2CYP2D6KDM4ELMNACHRM2 | |
| SCHEMBL10995440 | 0.74 | KDM4E (0.49) | CYP1A2CYP2D6KDM4ECYP3A4TSHR | |
| Flavoxate SCHEMBL1650335 | 0.74 | LMNA (0.96) | CYP1A2CYP2D6KDM4ELMNACHRM2 | |
| SCHEMBL10550674 | 0.73 | KDM4E (0.60) | CYP1A2CYP2D6KDM4ELMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0374210-A1 | FLEVOXATE AND DERIVATIVES FOR ERECTILE DYSFUNCTIONS | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1990-06-27 | — | — | EP | disclosed |
| WO-1989010123-A1 | FLEVOXATE AND DERIVATIVES FOR ERECTILE DYSFUNCTIONS | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1989-11-02 | — | — | WO | disclosed |