Flavoxate

Flavoxate

SCHEMBL25801

Cc1c(-c2ccccc2)oc2c(C(=O)OCCN3CCCCC3)cccc2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PDE4APDE4BPDE4CPDE4DPDE7APDE7BPDE8APDE8B

The experimentally established mechanism targets of Flavoxate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A known ✓ P27815 1/20 1.00
LMNA P02545 5/20 1.00
HTR1A P08908 3/20 1.00
ADRA1A P35348 3/20 1.00
KDM4E B2RXH2 1/20 1.00
CYP1A2 P05177 1/20 1.00
CHRM2 P08172 1/20 1.00
CYP3A4 P08684 1/20 1.00
ADRA2A P08913 1/20 1.00
ADORA3 P0DMS8 1/20 1.00
CYP2D6 P10635 1/20 1.00
CHRM1 P11229 1/20 1.00
ACHE P22303 1/20 1.00
SLC6A2 P23975 1/20 1.00
OPRM1 P35372 1/20 1.00
DRD3 P35462 1/20 1.00
KCNH2 Q12809 1/20 1.00
HRH3 Q9Y5N1 1/20 1.00
ALDH1A1 P00352 4/20 0.58
MAPT P10636 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flavoxate SCHEMBL29421720 1.00 LMNA (1.00) LMNAHTR1AADRA1AKDM4ECYP1A2
Flavoxate SCHEMBL124540 0.99 LMNA (0.98) LMNAHTR1AADRA1AKDM4ECYP1A2
Flavoxate SCHEMBL29395220 0.99 LMNA (0.98) LMNAHTR1AADRA1AKDM4ECYP1A2
Flavoxate SCHEMBL1650335 0.98 LMNA (0.96) LMNAHTR1AADRA1AKDM4ECYP1A2
Flavoxate SCHEMBL7061192 0.95 LMNA (0.90) LMNAHTR1AADRA1AKDM4ECYP1A2
Hydrochloric Acid SCHEMBL10549683 0.92 LMNA (0.85) LMNAHTR1AADRA1AKDM4ECYP1A2
SCHEMBL10707910 0.91 LMNA (0.84) LMNAHTR1AADRA1AKDM4ECYP1A2
Hydrochloric Acid SCHEMBL11035366 0.91 LMNA (0.83) LMNAHTR1AADRA1AKDM4ECYP1A2
Hydrochloric Acid SCHEMBL10709825 0.91 LMNA (0.83) LMNAHTR1AADRA1AKDM4ECYP1A2
Hydrochloric Acid SCHEMBL10710690 0.89 LMNA (0.80) LMNAHTR1AADRA1AKDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6859 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638459-B2 Method of diagnosing overactive bladder disorder UNIVERSITY OF PORTSMOUTH HIGHER EDUCATION CORPORATION (GB) 2026-05-26 US claimed
EP-4717276-A2 OPHTHALMIC COMPOSITIONS COMPRISING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER University of Canberra (AU) 2026-04-01 EP claimed
EP-3346842-B1 STABLE INOCULANT COMPOSITIONS AND METHODS FOR PRODUCING SAME NOVONESIS PLANT BIOSOLUTIONS AS (DK) 2026-03-25 EP claimed
EP-4706766-A2 TOPICAL OPHTHALMOLOGICAL COMPOSITIONS ADS Therapeutics LLC (US) 2026-03-11 EP claimed
EP-4680203-A1 COMPOSITIONS FOR SUSTAINED RELEASE OF POORLY SOLUBLE ACTIVE INGREDIENTS Prolevi Bio AB (SE) 2026-01-21 EP claimed
US-12496357-B2 Compositions and methods for treating sickle cell disease YALE UNIVERSITY (US) 2025-12-16 US claimed
US-12485177-B2 Topical ophthalmological compositions ADS THERAPEUTICS LLC (US) 2025-12-02 US claimed
EP-3442516-B1 OPHTHALMIC COMPOSITIONS COMPRISING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER UNIV CANBERRA (AU) 2025-11-12 EP claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
US-20250144056-A1 ANTIMICROBIAL HOST DEFENSE PEPTIDE-INDUCING COMPOSITIONS AND METHODS OF PRODUCTION AND USE THEREOF BOARD OF REGENTS FOR THE OKLAHOMA AGRICULTURAL AND MECH COLLEGES (US) 2025-05-08 US claimed
US-5266347-A Preparing in fermentation broth; drying; separating; adding to feed to prevent fungal attack during storage DUCOA L.P. (US) 1993-11-30 US claimed
US-5165937-A Urinary disorders RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 1992-11-24 US claimed
WO-1992015305-A1 METHOD OF TREATMENT FOR ASTHMA, BRONCHOSPASM AND OBSTRUCTIVE LUNG DISEASE BAKER CUMMINS PHARMACEUTICALS, INC. (US) 1992-09-17 WO claimed
EP-0250374-B1 THERAPEUTIC SYSTEM FOR CONTROLLED RELEASE OF DRUGS RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. (IT) 1991-05-02 EP claimed
EP-0393572-A2 Controlled release tablets containing flavoxate RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1990-10-24 EP claimed
EP-0356192-A2 Prevention & treatment of liver abscesses in animals SMITHKLINE BEECHAM CORPORATION (US) 1990-02-28 EP claimed
US-4769236-A Medicaments with a high degree of solubility and method for their production ELAN CORPORATION, PLC (IE) 1988-09-06 US claimed
EP-0250374-A1 Therapeutic system for controlled release of drugs RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. (IT) 1987-12-23 EP claimed
EP-0063490-A1 Lactation improvement method ELI LILLY AND COMPANY (US) 1982-10-27 EP claimed
US-4336250-A VIRGINIAMYCIN OR ELFAMYCIN ANTIBIOTICS ELI LILLY AND COMPANY (US) 1982-06-22 US claimed