SCHEMBL1035300

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1034835	0.87	SIRT2 (0.51)	LMNAMAPTHPGDEGFRKDR
	SCHEMBL1031038	0.86	LMNA (0.48)	LMNAMAPTHPGDEGFRKDR
	SCHEMBL1034400	0.86	LMNA (0.64)	LMNAMAPTHPGDMEN1KMT2A
	SCHEMBL1031211	0.83	PARP1 (0.52)	PARP1PIK3CDPIK3CAPIK3CGMEN1
	SCHEMBL1034424	0.82	CSF1R (0.52)	LMNAMAPTPARP1KDRMEN1
	SCHEMBL1035120	0.82	SIRT2 (0.48)	LMNAMAPTHPGDPARP1EGFR
	SCHEMBL1033886	0.81	LMNA (0.47)	LMNAMAPTHPGDEGFRKDR
	SCHEMBL1077022	0.81	MPL (0.51)	PARP1PIK3CDPIK3CAPIK3CGMPL
	SCHEMBL1031208	0.81	SCN9A (0.48)	LMNAMAPTHPGDEGFRKDR
	SCHEMBL1935556	0.80	SCN9A (0.45)	LMNAMAPTHPGDEGFRKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.