SCHEMBL10353295

SCHEMBL10353295

c1ccc2cc(-c3c4ccccc4c(-c4ccc5ccccc5c4)c4cc(-c5ccc(-c6cn7cccnc7n6)cc5)ccc34)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 15/20 0.56
▸ KDM4E B2RXH2 14/20 0.56
▸ HPGD P15428 8/20 0.56
▸ GLA P06280 7/20 0.56
▸ HSD17B10 Q99714 3/20 0.56
▸ RAB9A P51151 12/20 0.53
▸ GAA P10253 9/20 0.53
▸ NPC1 O15118 9/20 0.53
▸ SMN1; SMN2 Q16637 6/20 0.53
▸ MAPT P10636 5/20 0.53
▸ KMT2A Q03164 4/20 0.53
▸ MEN1 O00255 3/20 0.53
▸ TP53 P04637 1/20 0.53
▸ POLB P06746 2/20 0.53
▸ CDC7 O00311 1/20 0.48
▸ DAPK3 O43293 1/20 0.48
▸ DYRK3 O43781 1/20 0.48
▸ ROCK2 O75116 1/20 0.48
▸ PRKD3 O94806 1/20 0.48
▸ CDK1 P06493 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL970705 0.93 ALDH1A1 (0.62) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL10354057 0.90 ALDH1A1 (0.68) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL13029579 0.88 ALDH1A1 (0.70) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL13821046 0.85 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL13821056 0.85 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL10353748 0.83 KDM4E (0.35) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL13821064 0.83 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL10353272 0.82 RAB9A (0.52) ALDH1A1KDM4EHPGDHSD17B10RAB9A
SCHEMBL14461520 0.82 ALDH1A1 (0.55) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL25112861 0.82 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDGLAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910563-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-02-02 — — US disclosed
US-20170324042-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-09 — — US disclosed
US-20170324042-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-09 — — US disclosed
US-9012042-B2 Condensed-cyclic compound, organic light-emitting device comprising the same, and flat panel display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2015-04-21 — — US disclosed
US-9012042-B2 Condensed-cyclic compound, organic light-emitting device comprising the same, and flat panel display apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2015-04-21 — — US disclosed
US-8999525-B2 Condensed-cyclic compound, organic light-emitting device comprising the same, and flat panel display apparatus including the device SAMSUNG DISPLAY CO., LTD. (KR) 2015-04-07 — — US disclosed
US-8999525-B2 Condensed-cyclic compound, organic light-emitting device comprising the same, and flat panel display apparatus including the device SAMSUNG DISPLAY CO., LTD. (KR) 2015-04-07 — — US disclosed
EP-2157627-B1 Organic light emitting diode including light-efficiency-improvement layer SAMSUNG DISPLAY CO LTD (KR) 2013-01-23 — — EP disclosed
US-8343638-B2 Organic light emitting diode including light-efficiency-improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2013-01-01 — — US disclosed
US-8343638-B2 Organic light emitting diode including light-efficiency-improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2013-01-01 — — US disclosed
US-20120181922-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-19 — — US disclosed
US-7824780-B2 Imidazopyrimidine-based compound and organic light-emitting device employing organic layer including the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-11-02 — — US disclosed
US-7824780-B2 Imidazopyrimidine-based compound and organic light-emitting device employing organic layer including the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-11-02 — — US disclosed
EP-2157627-A1 Organic light emitting diode including light-efficiency-improvement layer Samsung Mobile Display Co., Ltd. (KR) 2010-02-24 — — EP disclosed
US-20100039029-A1 Organic Light Emitting Diode Including Light-Efficiency-Improvement Layer SAMSUNG DISPLAY CO., LTD. (KR) 2010-02-18 — — US disclosed
US-20100039029-A1 Organic Light Emitting Diode Including Light-Efficiency-Improvement Layer SAMSUNG DISPLAY CO., LTD. (KR) 2010-02-18 — — US disclosed
EP-1970376-B1 Imidazopyrimidine-based compound and organic light-emitting device employing organic layer including the same SAMSUNG MOBILE DISPLAY CO LTD (KR) 2009-11-18 — — EP disclosed
US-20080226945-A1 IMIDAZOPYRIMIDINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING ORGANIC LAYER INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2008-09-18 — — US disclosed
US-20080226945-A1 IMIDAZOPYRIMIDINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING ORGANIC LAYER INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2008-09-18 — — US disclosed
EP-1970376-A1 Imidazopyrimidine-based compound and organic light-emitting device employing organic layer including the same Samsung SDI Co., Ltd. (KR) 2008-09-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170324042-A1 ORGANIC LIGHT-EMITTING DEVICE L1CAM, OR10J3, ORAI2 ALDH1A1 21/4885KDM4E 3333/4885HPGD 3203/4885
US-10910563-B2 Organic light-emitting device L1CAM, OR10J3, ORAI2 ALDH1A1 21/4885KDM4E 3333/4885HPGD 3203/4885
US-20080226945-A1 IMIDAZOPYRIMIDINE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING ORGANIC LAYER INCLUDING THE SAME TPMT, DPYD, TYMP ALDH1A1 458/4885KDM4E 1056/4885HPGD 2595/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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