Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.72 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13742655 | 0.84 | PTPN1 (1.00) | PTPN1IDO1PTPN2ALDH1A1CYP3A4 | |
| SCHEMBL3951930 | 0.77 | SLC10A1 (0.56) | PTPN1SLC10A1GPBAR1 | |
| SCHEMBL19185380 | 0.72 | PTPN1 (0.62) | PTPN1IDO1PTPN2ALDH1A1CYP3A4 | |
| SCHEMBL19487085 | 0.71 | PTPN1 (0.61) | PTPN1IDO1PTPN2ALDH1A1CYP3A4 | |
| SCHEMBL14345016 | 0.71 | PTPN1 (0.57) | PTPN1SLC10A1USP7GPBAR1PRKCD | |
| SCHEMBL25464072 | 0.70 | PTPN1 (0.56) | PTPN1PTPN2USP7GPBAR1PRKCD | |
| SCHEMBL14345254 | 0.70 | LMNA (0.48) | PTPN1PTPN2GPBAR1 | |
| SCHEMBL14345996 | 0.70 | LMNA (0.48) | PTPN1PTPN2GPBAR1 | |
| SCHEMBL19338147 | 0.70 | LMNA (0.48) | PTPN1PTPN2GPBAR1 | |
| SCHEMBL28174220 | 0.69 | PTPN1 (0.58) | PTPN1IDO1SLC10A1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276493-A1 | ANTIOXIDANT INFLAMMATION MODULATORS: OLEANOLIC ACID DERIVATIVES WITH AMINO AND OTHER MODIFICATIONS AT C-17 | Reata Pharmaceuticals, Inc. (US) | 2011-01-26 | — | — | EP | claimed |
| WO-2009129546-A1 | ANTIOXIDANT INFLAMMATION MODULATORS: OLEANOLIC ACID DERIVATIVES WITH AMINO AND OTHER MODIFICATIONS AT C-17 | REATA PHARMACEUTICALS, INC. (US) | 2009-10-22 | — | — | WO | claimed |