Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.44 |
| ▸ | ACP1 | P24666 | 2/20 | 0.44 |
| ▸ | PTPRF | P10586 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.35 |
| ▸ | IL1B | P01584 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345254 | 1.00 | LMNA (0.48) | LMNASMN1; SMN2NT5EGPBAR1PTPN1 | |
| SCHEMBL14345996 | 1.00 | LMNA (0.48) | LMNASMN1; SMN2NT5EGPBAR1PTPN1 | |
| SCHEMBL18688129 | 0.87 | LMNA (0.47) | LMNASMN1; SMN2NT5EGPBAR1PTPN1 | |
| SCHEMBL13759951 | 0.83 | LMNA (0.52) | LMNASMN1; SMN2NT5EGPBAR1PTPN1 | |
| SCHEMBL13759952 | 0.83 | LMNA (0.52) | LMNASMN1; SMN2NT5EGPBAR1PTPN1 | |
| SCHEMBL21149779 | 0.81 | LMNA (0.53) | LMNASMN1; SMN2NT5EGPBAR1PTPN1 | |
| SCHEMBL19338168 | 0.81 | LMNA (0.50) | LMNASMN1; SMN2NT5EGPBAR1PTPN1 | |
| SCHEMBL15202809 | 0.81 | GPBAR1 (0.50) | LMNASMN1; SMN2NT5EGPBAR1PTPN1 | |
| SCHEMBL17761431 | 0.81 | GPBAR1 (0.50) | LMNASMN1; SMN2NT5EGPBAR1PTPN1 | |
| SCHEMBL13403269 | 0.81 | GPBAR1 (0.50) | LMNASMN1; SMN2NT5EGPBAR1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814834-B1 | C-3 CYCLOALKENYL TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | VIIV HEALTHCARE UK (NO 5) LTD (GB) | 2017-09-13 | — | — | EP | disclosed |