Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 6/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13019549 | 0.91 | MAPK1 (0.50) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL11764947 | 0.82 | MAPK1 (0.62) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL10827122 | 0.81 | KMT2A (0.48) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL15031934 | 0.79 | MAPK1 (0.59) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL10083544 | 0.77 | BCHE (0.60) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL15007308 | 0.77 | MAPK1 (0.53) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL1208061 | 0.74 | MAPK1 (0.67) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29557693 | 0.74 | MAPK1 (0.67) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL8224985 | 0.74 | MAPK1 (0.59) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL24860289 | 0.73 | MAPK1 (0.65) | MAPK1MEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170188-B1 | NOVEL PHENOTHIAZINES, PREPARATION THEREOF AND USE THEREOF IN ELECTROCHROMIC RECORDING SYSTEMS | THE HILTON - DAVIS CHEMICAL COMPANY (US) | 1990-08-29 | — | — | EP | claimed |
| US-4652643-A | LEUCO DYES | THE HILTON-DAVIS CHEMICAL COMPANY (US) | 1987-03-24 | — | — | US | claimed |
| EP-0170188-A1 | Novel phenothiazines, preparation thereof and use thereof in electrochromic recording systems | THE HILTON - DAVIS CHEMICAL COMPANY (US) | 1986-02-05 | — | — | EP | claimed |
| US-4561001-A | SUPPORT SHEET CONTAING PHENOTHIAZINE COLOR FORMER | THE HILTON-DAVIS CHEMICAL CO. (US) | 1985-12-24 | — | — | US | claimed |