Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BCL9 | O00512 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10353754 | 0.81 | MAPK1 (0.52) | KMT2AMAPK1MEN1TDP1L3MBTL1 | |
| SCHEMBL11764947 | 0.78 | MAPK1 (0.62) | KMT2AMAPK1MEN1TDP1L3MBTL1 | |
| SCHEMBL10827710 | 0.76 | MAPK1 (0.54) | KMT2AMAPK1MEN1TDP1L3MBTL1 | |
| SCHEMBL13019549 | 0.75 | MAPK1 (0.50) | KMT2AMAPK1MEN1TDP1L3MBTL1 | |
| SCHEMBL15031934 | 0.75 | MAPK1 (0.59) | KMT2AMAPK1MEN1TDP1L3MBTL1 | |
| SCHEMBL7401871 | 0.73 | BCL9 (0.57) | KMT2AMAPK1MEN1TDP1LMNA | |
| SCHEMBL10083544 | 0.73 | BCHE (0.60) | KMT2AMAPK1MEN1TDP1L3MBTL1 | |
| SCHEMBL15007308 | 0.73 | MAPK1 (0.53) | KMT2AMAPK1MEN1TDP1L3MBTL1 | |
| SCHEMBL21752026 | 0.72 | SNCA (0.69) | KMT2AMAPK1MEN1TDP1L3MBTL1 | |
| SCHEMBL9008999 | 0.71 | L3MBTL1 (0.67) | KMT2AMAPK1MEN1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604458-A | CHROMOGENS FOR ELECTROCHROMIC RECORDING SYSTEMS | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-08-05 | — | — | US | claimed |
| EP-0170189-A1 | Novel phenothiazines, preparation thereof and use thereof in electrochromic recording systems | THE HILTON - DAVIS CHEMICAL COMPANY (US) | 1986-02-05 | — | — | EP | claimed |
| US-4551740-A | PHENOTHIAZINE | THE HILTON-DAVIS CHEMICAL CO. (US) | 1985-11-05 | — | — | US | claimed |
| US-4604458-A | CHROMOGENS FOR ELECTROCHROMIC RECORDING SYSTEMS | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0170189-A1 | Novel phenothiazines, preparation thereof and use thereof in electrochromic recording systems | THE HILTON - DAVIS CHEMICAL COMPANY (US) | 1986-02-05 | — | — | EP | disclosed |
| US-4551740-A | PHENOTHIAZINE | THE HILTON-DAVIS CHEMICAL CO. (US) | 1985-11-05 | — | — | US | disclosed |