Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1208061 | 0.93 | MAPK1 (0.67) | MAPK1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29557693 | 0.93 | MAPK1 (0.67) | MAPK1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10353761 | 0.86 | MAPK1 (0.51) | MAPK1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL21752063 | 0.86 | SNCA (0.60) | MAPK1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1926806 | 0.86 | NOX1 (0.69) | MAPK1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL20737960 | 0.83 | MAPK1 (0.56) | MAPK1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11595006 | 0.83 | MAPK1 (0.56) | MAPK1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10353757 | 0.82 | MEN1 (0.42) | MAPK1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL21752026 | 0.82 | SNCA (0.69) | MAPK1TDP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL18408661 | 0.82 | MAPK1 (0.55) | MAPK1TDP1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170188-B1 | NOVEL PHENOTHIAZINES, PREPARATION THEREOF AND USE THEREOF IN ELECTROCHROMIC RECORDING SYSTEMS | THE HILTON - DAVIS CHEMICAL COMPANY (US) | 1990-08-29 | — | — | EP | claimed |
| US-4652643-A | LEUCO DYES | THE HILTON-DAVIS CHEMICAL COMPANY (US) | 1987-03-24 | — | — | US | claimed |
| EP-0170188-A1 | Novel phenothiazines, preparation thereof and use thereof in electrochromic recording systems | THE HILTON - DAVIS CHEMICAL COMPANY (US) | 1986-02-05 | — | — | EP | claimed |
| US-4561001-A | SUPPORT SHEET CONTAING PHENOTHIAZINE COLOR FORMER | THE HILTON-DAVIS CHEMICAL CO. (US) | 1985-12-24 | — | — | US | claimed |
| EP-3121169-B1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LAB LTD (SG) | 2022-02-09 | — | — | EP | disclosed |
| US-20210322435-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | Wis Ta Laboratories Ltd. (SG) | 2021-10-21 | — | — | US | disclosed |
| US-11045477-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2021-06-29 | — | — | US | disclosed |
| US-20200261465-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2020-08-20 | — | — | US | disclosed |
| US-9980971-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2018-05-29 | — | — | US | disclosed |
| US-9980971-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2018-05-29 | — | — | US | disclosed |
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2017-09-28 | — | — | US | disclosed |
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2017-09-28 | — | — | US | disclosed |
| EP-2457905-A1 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | Wista Laboratories Ltd. (SG) | 2012-05-30 | — | — | EP | disclosed |
| US-20110294795-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. | 2011-12-01 | — | — | US | disclosed |
| US-20110294795-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. | 2011-12-01 | — | — | US | disclosed |
| US-7956183-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2011-06-07 | — | — | US | disclosed |
| US-7956183-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | WISTA LABORATORIES LTD. (SG) | 2011-06-07 | — | — | US | disclosed |
| US-20090259040-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2009-10-15 | — | — | US | disclosed |
| US-20090259040-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2009-10-15 | — | — | US | disclosed |
| WO-2008007074-A2 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | WISTA LABORATORIES LTD. (SG) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170273986-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MB, TPMT, HBB | MAPK1 3258/4885TDP1 1840/4885MEN1 330/4885 |
| US-20210322435-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MB, TPMT, HBB | MAPK1 3258/4885TDP1 1840/4885MEN1 330/4885 |
| US-11045477-B2 | Methods of synthesis and/or purification of diaminophenothiazinium compounds | MB, TPMT, HBB | MAPK1 3258/4885TDP1 1840/4885MEN1 330/4885 |
| US-20090259040-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | PARK7, SNCA, GRN | MAPK1 3312/4885TDP1 583/4885MEN1 674/4885 |
| US-20110294795-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MMAB, MB, ABCB7 | MAPK1 2386/4885TDP1 3023/4885MEN1 20/4885 |
| US-20200261465-A1 | METHODS OF SYNTHESIS AND/OR PURIFICATION OF DIAMINOPHENOTHIAZINIUM COMPOUNDS | MB, TPMT, HBB | MAPK1 3258/4885TDP1 1840/4885MEN1 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.