SCHEMBL10354445

SCHEMBL10354445

O=C1OCC(c2ccc(Cl)cc2)O1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.40
POLB P06746 2/20 0.39
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX12 P18054 2/20 0.39
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HSD17B10 Q99714 1/20 0.39
LDHA P00338 1/20 0.38
RAB9A P51151 1/20 0.36
GUSB P08236 1/20 0.36
MAOB P27338 2/20 0.36
LTA4H P09960 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
SAE1 Q9UBE0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17053670 0.90 LTA4H (0.38) LTA4H
SCHEMBL17085395 0.81 MAOB (0.45) ALDH1A1HTTRAB9AMAOBLTA4H
SCHEMBL16463269 0.81 MAOB (0.45) MAOBLTA4H
SCHEMBL1239871 0.81 CYP2C9 (0.40) TAAR1POLBSLC6A2SLC6A4SLC6A3
SCHEMBL272449 0.80 TSHR (0.52) HSD17B10MAOBLTA4HKDM4E
SCHEMBL15396044 0.80 TSHR (0.52) HSD17B10MAOBLTA4HKDM4E
SCHEMBL16464223 0.77 HTR2C (0.39)
SCHEMBL28992539 0.77 HTR2A (0.36) MAOBLTA4H
SCHEMBL5959243 0.77 MAOB (0.49) SLC6A2SLC6A4SLC6A3ALOX12SMN1; SMN2
SCHEMBL17053669 0.74 FFAR1 (0.40) POLBRAB9AKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2903974-B1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENT & IND RES AN INDIAN REGISTERED BODY INC UNDER THE REGISTRATION OF SOCIETIES ACT AC (IN) 2016-11-23 EP claimed
US-9266854-B2 One step process for synthesis of cyclic carbonates COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-02-23 US claimed
US-20150259318-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-09-17 US claimed
EP-2903974-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES Council of Scientific & Industrial Research An Indian registered body incorporated under the Registration of Societies Act (Act XXI of 1860) (IN) 2015-08-12 EP claimed
WO-2014057500-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED (IN) 2014-04-17 WO claimed
CN-119638616-A Amino-bridged triaryloxy rare earth metal complex and preparation method and application thereof 苏州大学 2025-03-18 CN disclosed
US-20220135508-A1 Pyrogallol[2]resorcin[2]arene UNIVERSITY OF CINCINNATI (US) 2022-05-05 US disclosed
CN-105451775-B Drug antibody conjugate 法马马有限公司 2019-09-06 CN disclosed
EP-2903974-B1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENT & IND RES AN INDIAN REGISTERED BODY INC UNDER THE REGISTRATION OF SOCIETIES ACT AC (IN) 2016-11-23 EP disclosed
EP-2903974-B1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENT & IND RES AN INDIAN REGISTERED BODY INC UNDER THE REGISTRATION OF SOCIETIES ACT AC (IN) 2016-11-23 EP disclosed
US-9266854-B2 One step process for synthesis of cyclic carbonates COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-02-23 US disclosed
US-20150259318-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-09-17 US disclosed
US-20150259318-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-09-17 US disclosed
US-20150259318-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-09-17 US disclosed
EP-2903974-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES Council of Scientific & Industrial Research An Indian registered body incorporated under the Registration of Societies Act (Act XXI of 1860) (IN) 2015-08-12 EP disclosed
WO-2014057500-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED (IN) 2014-04-17 WO disclosed
WO-2014057500-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED (IN) 2014-04-17 WO disclosed
EP-0390777-A1 CYCLOCARBONATE COMPOUNDS DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-10-10 EP disclosed
WO-1989000565-A1 CYCLOCARBONATE COMPOUNDS DAINIPPON INK & CHEMICALS, INC. (JP) 1989-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259318-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES CDY1; CDY1B, CA4, CCNY TAAR1 3240/4885POLB 1275/4885SLC6A2 3959/4885
US-20220135508-A1 Pyrogallol[2]resorcin[2]arene AGL, PGLS, MGAM TAAR1 4494/4885POLB 2987/4885SLC6A2 4534/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.