Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 9/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068132 | 0.84 | NFE2L2 (0.36) | NFE2L2KDM4EMPIL3MBTL1NPC1 | |
| SCHEMBL30345232 | 0.82 | NFE2L2 (0.38) | NFE2L2KDM4EMPIL3MBTL1NPC1 | |
| SCHEMBL9065844 | 0.82 | NFE2L2 (0.38) | NFE2L2KDM4EMPIL3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL28284403 | 0.80 | NFE2L2 (0.37) | NFE2L2KDM4EMPIL3MBTL1NPC1 | |
| SCHEMBL10354554 | 0.78 | CYP19A1 (0.35) | NFE2L2KDM4EL3MBTL1CYP19A1PDE4B | |
| SCHEMBL3914027 | 0.78 | NFE2L2 (0.33) | NFE2L2KDM4EMPIL3MBTL1 | |
| SCHEMBL5958366 | 0.76 | TRPV1 (0.37) | NFE2L2KDM4EMPIL3MBTL1 | |
| SCHEMBL10763328 | 0.75 | NFE2L2 (0.35) | NFE2L2KDM4EMPIL3MBTL1 | |
| SCHEMBL25189938 | 0.74 | L3MBTL1 (0.34) | NFE2L2KDM4EMPIL3MBTL1NAPRT | |
| SCHEMBL12293799 | 0.72 | MAPT (0.35) | NFE2L2KDM4EMPIL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110690-B1 | PREPARATION OF (TRIFLUOROMETHYL)PYRIDINES | THE DOW CHEMICAL COMPANY (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4650875-A | CATALYTIC FLUORINATION OF TRICHLOROMETHYL ANALOG | THE DOW CHEMICAL COMPANY (US) | 1987-03-17 | — | — | US | disclosed |
| US-4590279-A | CATALYTIC FLUORINATION OF (TRICHLOROMETHYL)PYRIDINES | THE DOW CHEMICAL COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| US-4546192-A | Chlorine exchange for fluorine in ring-fluorinated pyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1985-10-08 | — | — | US | disclosed |
| EP-0110690-A1 | Preparation of (trifluoromethyl)pyridines | THE DOW CHEMICAL COMPANY (US) | 1984-06-13 | — | — | EP | disclosed |