Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | CCR8 | P51685 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10354999 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2L3MBTL1TDP1AHRKDM4E | |
| SCHEMBL27895794 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1TDP1AHRKDM4E | |
| SCHEMBL29424134 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1TDP1AHRKDM4E | |
| SCHEMBL29401687 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1TDP1AHRKDM4E | |
| SCHEMBL84051 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1TDP1AHRKDM4E | |
| SCHEMBL5041519 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2L3MBTL1TDP1AHRKDM4E | |
| SCHEMBL28849911 | 0.80 | L3MBTL1 (0.58) | SMN1; SMN2L3MBTL1TDP1KDM4ELMNA | |
| SCHEMBL30689472 | 0.80 | L3MBTL1 (0.58) | SMN1; SMN2L3MBTL1TDP1KDM4ELMNA | |
| SCHEMBL2331251 | 0.80 | L3MBTL1 (0.58) | SMN1; SMN2L3MBTL1TDP1KDM4ELMNA | |
| SCHEMBL21742216 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1TDP1AHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988101-B | Synthesis method of 2-fluoro-6-trifluoromethylpyridine | 沈阳化工研究院有限公司 | 2022-06-07 | — | — | CN | disclosed |
| EP-0110690-B1 | PREPARATION OF (TRIFLUOROMETHYL)PYRIDINES | THE DOW CHEMICAL COMPANY (US) | 1990-09-26 | — | — | EP | disclosed |
| EP-0183228-A2 | Chlorine exchange for fluorine in 2-fluoro-pyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1986-06-04 | — | — | EP | disclosed |
| US-4590279-A | CATALYTIC FLUORINATION OF (TRICHLOROMETHYL)PYRIDINES | THE DOW CHEMICAL COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| US-4567274-A | TRICHLOROMETHYL OR DICHLORFLUOROMETHLPICOLINE | THE DOW CHEMICAL COMPANY (US) | 1986-01-28 | — | — | US | disclosed |
| US-4546192-A | Chlorine exchange for fluorine in ring-fluorinated pyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1985-10-08 | — | — | US | disclosed |
| US-4493932-A | Chlorine exchange for fluorine in 2-fluoro-pyridine compounds | THE DOW CHEMICAL COMPANY (US) | 1985-01-15 | — | — | US | disclosed |
| EP-0110690-A1 | Preparation of (trifluoromethyl)pyridines | THE DOW CHEMICAL COMPANY (US) | 1984-06-13 | — | — | EP | disclosed |