SCHEMBL10354511

SCHEMBL10354511

O=C(O)CCCCC(NC(=O)COc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR34 Q9UPC5 3/20 0.54
RECQL P46063 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
FOLH1 Q04609 5/20 0.49
MAPT P10636 1/20 0.48
ATF4 P18848 3/20 0.48
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
PTPN2 P17706 1/20 0.47
PTPN1 P18031 1/20 0.47
CDC25B P30305 1/20 0.47
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10355094 0.96 GPR34 (0.55) GPR34RECQLSMN1; SMN2FOLH1MAPT
SCHEMBL10610621 0.91 GPR34 (0.57) GPR34RECQLSMN1; SMN2FOLH1MAPT
SCHEMBL4599881 0.88 GPR34 (0.54) GPR34RECQLSMN1; SMN2MAPTATF4
SCHEMBL4599884 0.88 GPR34 (0.54) GPR34RECQLSMN1; SMN2MAPTATF4
SCHEMBL10355096 0.86 GPR34 (0.53) GPR34RECQLSMN1; SMN2MAPTKMT2A
SCHEMBL10354480 0.86 GPR34 (0.55) GPR34RECQLSMN1; SMN2MAPTKMT2A
SCHEMBL10872191 0.84 GPR34 (0.58) GPR34RECQLSMN1; SMN2MAPTATF4
SCHEMBL10872183 0.84 GPR34 (0.58) GPR34RECQLSMN1; SMN2MAPTATF4
SCHEMBL10354599 0.83 GPR34 (0.57) GPR34RECQLSMN1; SMN2MAPTKMT2A
SCHEMBL10354600 0.83 GPR34 (0.57) GPR34RECQLSMN1; SMN2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0205327-B1 PHENOXYACETYLAMIDE DERIVATIVE AND PROCESS FOR PRODUCTION AND USE THEREOF SUNTORY LIMITED (JP) 1990-09-26 EP disclosed
EP-0205327-A1 Phenoxyacetylamide derivative and process for production and use thereof SUNTORY LIMITED (JP) 1986-12-17 EP disclosed