SCHEMBL10354599

SCHEMBL10354599

CCC[C@H](NC(=O)COc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR34 Q9UPC5 3/20 0.57
SMN1; SMN2 Q16637 5/20 0.52
LMNA P02545 3/20 0.52
THRB P10828 2/20 0.52
ALDH1A1 P00352 4/20 0.52
KMT2A Q03164 4/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MAPT P10636 2/20 0.51
MEN1 O00255 2/20 0.50
RECQL P46063 1/20 0.50
PTPN2 P17706 1/20 0.49
PTPN1 P18031 1/20 0.49
CDC25B P30305 1/20 0.49
KDM4E B2RXH2 1/20 0.49
TP53 P04637 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10354600 1.00 GPR34 (0.57) GPR34SMN1; SMN2LMNATHRBALDH1A1
SCHEMBL10354480 0.92 GPR34 (0.55) GPR34SMN1; SMN2LMNATHRBALDH1A1
SCHEMBL10355096 0.90 GPR34 (0.53) GPR34SMN1; SMN2LMNATHRBALDH1A1
SCHEMBL10873775 0.89 GPR34 (0.59) GPR34SMN1; SMN2LMNATHRBALDH1A1
SCHEMBL10872191 0.88 GPR34 (0.58) GPR34SMN1; SMN2ALDH1A1KMT2AL3MBTL1
SCHEMBL10872183 0.88 GPR34 (0.58) GPR34SMN1; SMN2ALDH1A1KMT2AL3MBTL1
SCHEMBL10610621 0.86 GPR34 (0.57) GPR34SMN1; SMN2ALDH1A1KMT2AMAPT
SCHEMBL10610120 0.85 GPR34 (0.60) GPR34SMN1; SMN2ALDH1A1KMT2AL3MBTL1
SCHEMBL10355094 0.84 GPR34 (0.55) GPR34SMN1; SMN2ALDH1A1KMT2AMAPT
SCHEMBL10872638 0.84 ALDH1A1 (0.73) GPR34SMN1; SMN2LMNAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0205327-B1 PHENOXYACETYLAMIDE DERIVATIVE AND PROCESS FOR PRODUCTION AND USE THEREOF SUNTORY LIMITED (JP) 1990-09-26 EP disclosed
EP-0205327-A1 Phenoxyacetylamide derivative and process for production and use thereof SUNTORY LIMITED (JP) 1986-12-17 EP disclosed