Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 4/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507506 | 0.86 | KCNQ3 (0.44) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL41029 | 0.84 | KCNQ3 (0.53) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL29364836 | 0.84 | KCNQ3 (0.53) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL10951721 | 0.83 | KCNQ3 (0.41) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL4985623 | 0.81 | TSHR (0.41) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL31500776 | 0.81 | TSHR (0.41) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL14676854 | 0.80 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL21994672 | 0.80 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL9966941 | 0.80 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL17948247 | 0.80 | KCNQ3 (0.42) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284783-A | Liquid phase preparation of 2-chloro-5-trifluoromethylpyridine and 2-chloro-5-perchlorofluoromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-08-18 | — | — | US | claimed |
| US-4257857-A | Liquid phase preparation of 2-chloro-5-trifluoromethylpyridine and 2-chloro-5-perchlorofluoromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-03-24 | — | — | US | claimed |
| CN-107889486-B | Pyridin-2-ylpyridin/compounds and methods of use thereof | 日本曹达株式会社 | 2021-07-09 | — | — | CN | disclosed |
| US-10618882-B2 | Pyridine-2-yl pyridinium compound and method of using same | NIPPON SODA CO., LTD. (JP) | 2020-04-14 | — | — | US | disclosed |
| EP-3330253-B1 | PYRIDINE-2-YL-PYRIDINIUM COMPOUND AND METHOD OF USING SAME | NIPPON SODA CO (JP) | 2019-09-25 | — | — | EP | disclosed |
| EP-3330253-A1 | PYRIDINE-2-YL-PYRIDINIUM COMPOUND AND METHOD OF USING SAME | Nippon Soda Co., Ltd. (JP) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017018409-A1 | PYRIDINE-2-YL-PYRIDINIUM COMPOUND AND METHOD OF USING SAME | 日本曹達株式会社 | 2017-02-02 | — | — | WO | disclosed |
| EP-0110690-B1 | PREPARATION OF (TRIFLUOROMETHYL)PYRIDINES | THE DOW CHEMICAL COMPANY (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4925947-A | AGRICULTURAL USE, SENSITIVE TO CROPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0001473-B1 | HERBICIDAL HALOGENOMETHYL--PYRIDYLOXY-PHENOXY-ALKANECARBOXYLIC ACIDS AND DERIVATIVES, AND PROCESSES OF CONTROLLING UNWANTED PLANTS THEREWITH | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-27 | — | — | EP | disclosed |
| EP-0107866-B1 | TRIHALOMETHYLPYRIDINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-30 | — | — | EP | disclosed |
| EP-0014033-A2 | Halogenation of pyridine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-08-06 | — | — | EP | disclosed |
| EP-0013474-A2 | Preparation of 2-chloro-5-trifluoromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-07-23 | — | — | EP | disclosed |
| WO-1979000786-A1 | HERBICIDAL COMPOUNDS | ICI LTD (GB) | 1979-10-18 | — | — | WO | disclosed |
| EP-0004433-A1 | Herbicidal 2-(p-substituted-phenoxy)-pyridines and process for preparing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-10-03 | — | — | EP | disclosed |
| WO-1979000624-A1 | HERBICIDAL DERIVATIVES OF 2-(4(2-PYRIDYLOXY)PHENOXY)PROPANE,PROCESSES FOR PREPARING THEM,AND HERBICIDAL COMPOSITIONS CONTAINING THEM | ICI LTD (GB) | 1979-09-06 | — | — | WO | disclosed |
| EP-0003877-A1 | Herbicidal derivatives of 2-(4(2-pyridyloxy)phenoxy)propane, processes for preparing them, and herbicidal compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-09-05 | — | — | EP | disclosed |
| EP-0003648-A2 | 4-Aryloxy-substituted phenoxypropionamide derivatives useful as herbicides, compositions containing them, and processes for making them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-08-22 | — | — | EP | disclosed |
| EP-0001473-A2 | Herbicidal halogenomethyl--pyridyloxy-phenoxy-alkanecarboxylic acids and derivatives, and processes of controlling unwanted plants therewith | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-04-18 | — | — | EP | disclosed |
| WO-1979000094-A1 | HERBICIDAL PYRIDINE COMPOUNDS | ICI LTD (GB) | 1979-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10618882-B2 | Pyridine-2-yl pyridinium compound and method of using same | PNPO, PDXK, ABCB7 | KCNQ3 428/4885KCNQ2 182/4885KCNQ1 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.