Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 3/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364836 | 1.00 | KCNQ3 (0.53) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| Methylene Chloride SCHEMBL28144830 | 0.94 | GRM4 (0.49) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| Formaldehyde SCHEMBL28046297 | 0.94 | KCNQ3 (0.53) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL8115424 | 0.88 | KCNQ3 (0.45) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| Pyridine SCHEMBL28228735 | 0.87 | KCNQ3 (0.48) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL3370691 | 0.85 | NOS3 (0.46) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL10354550 | 0.84 | KCNQ3 (0.44) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL10507506 | 0.84 | KCNQ3 (0.44) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL29002068 | 0.84 | KCNQ3 (0.49) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 | |
| SCHEMBL1744141 | 0.83 | KIF11 (0.52) | KCNQ3KCNQ2KCNQ1KCNE1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3439 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688154-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - Portela & Ca., S.A. (PT) | 2026-02-11 | — | — | EP | claimed |
| CN-119661426-A | Method for synthesizing 2, 3-dichloro-5-trifluoromethyl pyridine in fixed bed reactor | 江苏优嘉植物保护有限公司 | 2025-03-21 | — | — | CN | claimed |
| WO-2025023851-A1 | MORPHOLINE OREXIN RECEPTOR ANTAGONISTS | BIAL - PORTELA & CA., S.A. (PT) | 2025-01-30 | — | — | WO | claimed |
| CN-115894351-B | Preparation method of metaflumuron intermediate etherate | 江苏天和制药有限公司 | 2024-07-23 | — | — | CN | claimed |
| CN-115772118-B | Preparation method of chlorfluazuron | 江苏天和制药有限公司 | 2024-07-02 | — | — | CN | claimed |
| EP-4105202-B1 | METHOD FOR PREPARING 2-CHLORO-5-TRIFLUOROMETHYLPYRIDINE | ZHEJIANG LANTIAN ENVIRONMENTAL PROT HI TECH CO LTD (CN) | 2024-05-01 | — | — | EP | claimed |
| CN-115282879-B | Raw material supply system and process for synthesizing 2-chloro-5-trifluoromethyl pyridine | 单县欣润化工有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-113527192-B | Preparation method of 2, 3-dichloro-5-trifluoromethyl pyridine | 武威广达科技有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-116178249-B | Ether derivative with insecticidal and acaricidal activities as well as preparation method and application thereof | 北京亦农生物科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-220416664-U | Tail gas absorbing device for 2-chloro-5-trifluoromethylpyridine production | 单县欣润化工有限公司 | 2024-01-30 | — | — | CN | claimed |
| EP-0065358-A1 | Production of 3-trichloromethyl- and 3-trifluoromethyl-pyridines | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-24 | — | — | EP | claimed |
| US-4288599-A | VAPOR PHASE HALOGENATION OF B-PICOLINE WITH CHLORINE AND HYDROGEN FLUORIDE | ISHIHARA SANGYO KAISHA LTD. (JP) | 1981-09-08 | — | — | US | claimed |
| US-4288600-A | VAPOR PHASE CHLORINATION | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-09-08 | — | — | US | claimed |
| US-4284783-A | Liquid phase preparation of 2-chloro-5-trifluoromethylpyridine and 2-chloro-5-perchlorofluoromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-08-18 | — | — | US | claimed |
| US-4275212-A | CONVERSION OF BIS(PYRIDINYL OXY) BENZENE BY-PRODUCTS WITH EXCESS HYDROQUINONE | THE DOW CHEMICAL COMPANY (US) | 1981-06-23 | — | — | US | claimed |
| US-4266064-A | CATALYTIC FLUORINATION IN A VAPOR PHASE | ISHIHARA SANGYO KAISHA LTD. (JP) | 1981-05-05 | — | — | US | claimed |
| US-4257857-A | Liquid phase preparation of 2-chloro-5-trifluoromethylpyridine and 2-chloro-5-perchlorofluoromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-03-24 | — | — | US | claimed |
| US-4249009-A | Processes for preparing 2-chloro-5-trifluoromethylpyridine | REILLY TAR & CHEMICAL CORP. (US) | 1981-02-03 | — | — | US | claimed |
| EP-0021453-A2 | 2-Chloro-5-trichloromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-01-07 | — | — | EP | claimed |
| EP-0013474-A2 | Preparation of 2-chloro-5-trifluoromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-07-23 | — | — | EP | claimed |