Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451456 | 0.97 | MAOA (0.74) | MAOAMAOBSIGMAR1L3MBTL1HTR2A | |
| SCHEMBL8096690 | 0.93 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL6546948 | 0.93 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL1226782 | 0.93 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL8094527 | 0.93 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL8095284 | 0.93 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL2823250 | 0.93 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL8085946 | 0.93 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT | |
| SCHEMBL6443055 | 0.93 | MAOA (0.70) | MAOAMAOBSIGMAR1L3MBTL1HTR2A | |
| SCHEMBL1433686 | 0.93 | SIGMAR1 (0.71) | MAOAMAOBSIGMAR1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253529-B1 | FLUORINATED POLYCYCLIC COMPOUNDS | ISC CHEMICALS LIMITED (GB) | 1990-09-26 | — | — | EP | disclosed |
| US-4895990-A | HIGH TEMPERATURE VAPOR SOLDERING FLUID, HEAT TRANSFER | I.S.C. CHEMICALS LIMITED (GB) | 1990-01-23 | — | — | US | disclosed |
| EP-0253529-A1 | Fluorinated polycyclic compounds | ISC CHEMICALS LIMITED (GB) | 1988-01-20 | — | — | EP | disclosed |