Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678684 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAHTTGAA | |
| SCHEMBL8875650 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAHTTGAA | |
| SCHEMBL8874396 | 0.84 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNAHTTGAA | |
| SCHEMBL9127426 | 0.82 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNAHTTGAA | |
| SCHEMBL8875433 | 0.80 | SMN1; SMN2 (0.60) | ALDH1A1KDM4ELMNAHTTGAA | |
| SCHEMBL13508800 | 0.79 | P2RX3 (0.53) | ALDH1A1KDM4ELMNAHTTGAA | |
| SCHEMBL9297717 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNAHTTGAA | |
| SCHEMBL2568138 | 0.74 | KDM4E (0.65) | ALDH1A1KDM4ELMNAHTTGAA | |
| SCHEMBL10600757 | 0.72 | NPC1 (0.62) | ALDH1A1KDM4ELMNAHTTGAA | |
| SCHEMBL3837069 | 0.71 | HDAC1 (0.51) | ALDH1A1KDM4ELMNAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222970-B1 | SULPHOALKYLATION PROCESS | Agfa-Gevaert AG (DE) | 1990-10-24 | — | — | EP | disclosed |
| US-4883880-A | Process for the preparation of sulfoalkyl quaternary salts and for the production of alkane sultones | AGFA-GEVAERT AKTIENGESSELLSCHAFT (DE) | 1989-11-28 | — | — | US | disclosed |
| US-4539408-A | Process for the preparation of sulphoalkyl quaternary salts | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1985-09-03 | — | — | US | disclosed |
| US-4504668-A | Process for the preparation of N-sulfoalkyl quaternary salts of nitrogen heterocyclics | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1985-03-12 | — | — | US | disclosed |
| EP-0064667-B1 | PROCESS FOR THE PREPARATION OF SULFOALKYL QUATERNARY SALTS | Agfa-Gevaert AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| EP-0034279-B1 | SULFOALKYLATING AGENTS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE MANUFACTURE OF QUANTERNARY SULFOALKYL SALTS | Agfa-Gevaert AG (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0064667-A1 | Process for the preparation of sulfoalkyl quaternary salts | Agfa-Gevaert AG (DE) | 1982-11-17 | — | — | EP | disclosed |
| EP-0055428-A1 | Bis-(3-sulfopropyl)ethers, process for their preparation and their use as alkylating agents for organic bases | Agfa-Gevaert AG (DE) | 1982-07-07 | — | — | EP | disclosed |
| US-4308390-A | Process for the production of sulphoalkyl quaternary salts | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1981-12-29 | — | — | US | disclosed |
| EP-0034279-A2 | Sulfoalkylating agents, process for their preparation and their use in the manufacture of quanternary sulfoalkyl salts | Agfa-Gevaert AG (DE) | 1981-08-26 | — | — | EP | disclosed |