Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 9/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.80 |
| ▸ | PGR | P06401 | 5/20 | 0.80 |
| ▸ | USP2 | O75604 | 4/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.74 |
| ▸ | AR | P10275 | 2/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.74 |
| ▸ | CNR1 | P21554 | 1/20 | 0.74 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | MMP1 | P03956 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10354654 | 1.00 | NR3C1 (0.80) | NR3C1CYP3A4PGRUSP2MEN1 | |
| SCHEMBL1217307 | 1.00 | NR3C1 (0.80) | NR3C1CYP3A4PGRUSP2MEN1 | |
| SCHEMBL10354655 | 1.00 | NR3C1 (0.80) | NR3C1CYP3A4PGRUSP2MEN1 | |
| Water SCHEMBL1219474 | 0.99 | NR3C1 (0.79) | NR3C1CYP3A4PGRUSP2MEN1 | |
| SCHEMBL6860007 | 0.97 | CYP3A4 (0.76) | NR3C1CYP3A4PGRUSP2MEN1 | |
| Beclomethasone 17-Monopropionate SCHEMBL10354253 | 0.93 | CYP3A4 (0.85) | NR3C1CYP3A4PGRUSP2MEN1 | |
| Beclomethasone 17-Monopropionate SCHEMBL102219 | 0.93 | CYP3A4 (0.85) | NR3C1CYP3A4PGRUSP2MEN1 | |
| Beclomethasone 17-Monopropionate SCHEMBL10354251 | 0.93 | CYP3A4 (0.85) | NR3C1CYP3A4PGRUSP2MEN1 | |
| Beclomethasone 17-Monopropionate SCHEMBL10354250 | 0.93 | CYP3A4 (0.85) | NR3C1CYP3A4PGRUSP2MEN1 | |
| SCHEMBL10865185 | 0.92 | CYP3A4 (0.84) | NR3C1CYP3A4PGRUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170500-B1 | NOVEL 9 ALPHA-FLUORO- OR CHLORO-CORTICOSTEROID ESTERS AND A PROCESS FOR THEIR PREPARATION | HOVIONE INTER LTD. (CH) | 1990-10-10 | — | — | EP | claimed |
| EP-0170500-A2 | Novel 9 alpha-fluoro- or chloro-corticosteroid esters and a process for their preparation | HOVIONE INTER LTD. (CH) | 1986-02-05 | — | — | EP | claimed |