SCHEMBL10355262

SCHEMBL10355262

CCC[C@H]1CC[C@H](C(C(=O)OCC)C(=O)OCC)CC1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
TSHR P16473 4/20 0.44
ALDH1A1 P00352 4/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KDM4E B2RXH2 1/20 0.36
CYP2C9 P11712 1/20 0.36
METAP2 P50579 1/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6838714 1.00 L3MBTL1 (0.50) L3MBTL1TSHRALDH1A1NPSR1KDM4E
SCHEMBL21500406 0.90 L3MBTL1 (0.47) L3MBTL1TSHRALDH1A1NPSR1KDM4E
SCHEMBL9209640 0.87 L3MBTL1 (0.61) L3MBTL1TSHRALDH1A1NPSR1KDM4E
SCHEMBL6839619 0.85 L3MBTL1 (0.53) L3MBTL1TSHRALDH1A1NPSR1KDM4E
SCHEMBL6839655 0.81 L3MBTL1 (0.56) L3MBTL1TSHRALDH1A1NPSR1KDM4E
SCHEMBL19853862 0.80 TSHR (0.47) L3MBTL1TSHRALDH1A1NPSR1CYP2C9
SCHEMBL7064929 0.79 MAPT (0.40) ALDH1A1CYP2C9LMNAMAPTTP53
SCHEMBL7064931 0.79 MAPT (0.40) ALDH1A1CYP2C9LMNAMAPTTP53
SCHEMBL12646819 0.79 L3MBTL1 (0.35) L3MBTL1TSHRALDH1A1NPSR1CYP2C9
SCHEMBL10021028 0.79 L3MBTL1 (0.35) L3MBTL1TSHRALDH1A1NPSR1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113233958-B Preparation method of 2- (trans-4-n-propylcyclohexyl) propane-1, 3-diol 阜阳欣奕华材料科技有限公司 2023-09-19 CN disclosed
CN-113233958-A Preparation method of 2- (trans-4-n-propylcyclohexyl) propane-1, 3-diol 阜阳欣奕华材料科技有限公司 2021-08-10 CN disclosed
EP-0152808-B1 NITROGEN CONTAINING HETEROCYCLES MERCK PATENT GmbH (DE) 1990-09-12 EP disclosed
US-4882082-A PYRIMIDINE DERIVATIVE LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-11-21 US disclosed
US-4752414-A LIQUID CRYSTAL PHASES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-06-21 US disclosed
EP-0152808-A2 Nitrogen containing heterocycles MERCK PATENT GmbH (DE) 1985-08-28 EP disclosed