Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064931 | 1.00 | MAPT (0.40) | MAPTCYP2C9TP53ALDH1A1LMNA | |
| SCHEMBL21500404 | 0.89 | MAPT (0.35) | MAPTCYP2C9TP53ALDH1A1LMNA | |
| SCHEMBL7866811 | 0.81 | CYP2C9 (0.41) | MAPTCYP2C9TP53ALDH1A1LMNA | |
| SCHEMBL10073273 | 0.81 | CYP2C9 (0.41) | MAPTCYP2C9TP53ALDH1A1LMNA | |
| Bicarbonate SCHEMBL9367749 | 0.80 | CYP2C9 (0.47) | MAPTCYP2C9TP53ALDH1A1LMNA | |
| SCHEMBL6838714 | 0.79 | L3MBTL1 (0.50) | MAPTCYP2C9TP53ALDH1A1LMNA | |
| SCHEMBL10355262 | 0.79 | L3MBTL1 (0.50) | MAPTCYP2C9TP53ALDH1A1LMNA | |
| SCHEMBL1645240 | 0.78 | CPN1 (0.33) | MAPTTP53ALDH1A1LMNAKMT2A | |
| SCHEMBL5616701 | 0.78 | CPN1 (0.33) | MAPTTP53ALDH1A1LMNAKMT2A | |
| Bicarbonate SCHEMBL27361683 | 0.76 | CYP2C9 (0.44) | MAPTCYP2C9TP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103030625-B | Binaphthol chipal compounds and preparation method thereof and application | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2015-09-16 | — | — | CN | disclosed |
| EP-1027403-B1 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | AVENTIS RES & TECH GMBH & CO (DE) | 2003-05-28 | — | — | EP | disclosed |
| US-6485797-B1 | 5-Arylindane derivatives and ferroelectric liquid crystal mixture containing same | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2002-11-26 | — | — | US | disclosed |
| EP-1027403-A2 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | Aventis Research & Technologies GmbH & Co. KG (DE) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999019420-A2 | 5-ARYLINDANE DERIVATIVES AND FERROELECTRIC LIQUID CRYSTAL MIXTURE CONTAINING SAME | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-04-22 | — | — | WO | disclosed |