SCHEMBL1035542

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1036232	0.86	SIRT2 (0.50)	EGFRFGFR1KDRSIRT2NPC1
	SCHEMBL1029917	0.83	EGFR (0.54)	EGFRFGFR1KDRSIRT2SLC40A1
	SCHEMBL1035290	0.82	NPC1 (0.55)	EGFRFGFR1KDRSIRT2NPC1
	SCHEMBL1029916	0.81	HDAC1 (0.52)	KDRSIRT2
	SCHEMBL1035313	0.79	IRAK4 (0.47)	NPC1RAB9AMAPTGAA
	SCHEMBL1029914	0.79	NPC1 (0.52)	NPC1RAB9AMAPTMEN1KMT2A
	SCHEMBL1030376	0.78	IRAK4 (0.47)	NPC1RAB9AMAPTMEN1KMT2A
	SCHEMBL1034300	0.78	GRM5 (0.44)	KDRSLC40A1NPC1RAB9AGRM5
	SCHEMBL1076614	0.78	HDAC1 (0.51)	EGFRNPC1RAB9AMEN1KMT2A
	SCHEMBL1035541	0.77	KAT6A (0.48)	KDRSIRT2RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.