SCHEMBL1035290

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1030617	0.86	ABL1 (0.52)	NPC1RAB9ADYRK1AABL1OPRM1
	SCHEMBL1034313	0.83	SLC40A1 (0.49)	NPC1RAB9AKDRDYRK1AABL1
	SCHEMBL1035542	0.82	EGFR (0.52)	NPC1RAB9AKDREGFRFGFR1
	SCHEMBL1029914	0.81	NPC1 (0.52)	NPC1RAB9ADYRK1AABL1OPRM1
	SCHEMBL1029917	0.81	EGFR (0.54)	NPC1RAB9AKDREGFRFGFR1
	SCHEMBL1029916	0.79	HDAC1 (0.52)	KDRDYRK1AABL1SIRT2
	SCHEMBL1032557	0.78	CYP3A4 (0.55)	DYRK1AKDM4EHSD17B10CYP11B1CYP11B2
	SCHEMBL1076614	0.77	HDAC1 (0.51)	NPC1RAB9AEGFRABL1KDM4E
	SCHEMBL13187196	0.77	ABL1 (0.48)	NPC1RAB9AABL1OPRM1KCNH2
	SCHEMBL1035313	0.76	IRAK4 (0.47)	NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.