Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.83 |
| ▸ | ARG2 | P78540 | 4/20 | 0.52 |
| ▸ | ARG1 | P05089 | 3/20 | 0.52 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.50 |
| ▸ | OTC | P00480 | 1/20 | 0.50 |
| ▸ | GLUL | P15104 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL11803679 | 1.00 | GSR (0.83) | GSRARG2ARG1RNPEPOTC | |
| Lysine SCHEMBL1825922 | 1.00 | GSR (0.83) | GSRARG2ARG1RNPEPOTC | |
| Lysine SCHEMBL1446119 | 1.00 | GSR (0.83) | GSRARG2ARG1RNPEPOTC | |
| Lysine SCHEMBL11799059 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPOTC | |
| Lysine SCHEMBL11670724 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPOTC | |
| Lysine SCHEMBL11801574 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPOTC | |
| Lysine SCHEMBL11671036 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPOTC | |
| Lysine SCHEMBL5444480 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPOTC | |
| Lysine SCHEMBL11798743 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPOTC | |
| Lysine SCHEMBL8143571 | 0.98 | GSR (0.80) | GSRARG2ARG1RNPEPOTC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707769-A | Method for preparing caprolactam by using fermentation liquor containing lysine, lysine or lysine salt as raw materials | 中国科学院长春应用化学研究所 | 2025-03-28 | — | — | CN | claimed |
| EP-4466102-A2 | E TO 1.5 PENTANEDIAMINE AND SEPARATION OF DIAMINES FROM AMINO AND CARBOXYLIC ACIDS | Archer Daniels Midland Company (US) | 2024-11-27 | — | — | EP | claimed |
| CN-118901938-A | Compound feed for improving production performance of Taihe black-bone chickens in growing period and application of compound feed | 浙江大学 | 2024-11-08 | — | — | CN | claimed |
| CN-118684627-A | Preparation method of dimethylamino caprolactam | 中国石油化工股份有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-118684625-A | Preparation method of functional caprolactam monomer | 中国石油化工股份有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-118684626-A | Method for synthesizing dimethylamino caprolactam | 中国石油化工股份有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-118613328-A | ETO 1.5 pentanediamine and separation of diamine from amino acids and carboxylic acids | 阿彻丹尼尔斯米德兰德公司 | 2024-09-06 | — | — | CN | claimed |
| CN-118515570-A | Method for synthesizing pentanediamine through photocatalysis | 龙子湖新能源实验室 | 2024-08-20 | — | — | CN | claimed |
| CN-115634711-B | Metal ion modified molecular sieve domain-limited transition metal nanoparticle and method for synthesizing pentanediamine by catalysis thereof | 郑州中科新兴产业技术研究院 | 2024-04-05 | — | — | CN | claimed |
| WO-2024023762-A1 | A STABLE LIQUID COMPOSITION OF OCRELIZUMAB | KASHIV BIOSCIENCES, LLC (US) | 2024-02-01 | — | — | WO | claimed |
| CN-112125810-A | Method for preparing pentamethylene diamine by catalyzing lysine decarboxylation with solid super acid | 郑州中科新兴产业技术研究院 | 2020-12-25 | — | — | CN | claimed |
| CN-111996219-A | Fermentation method of coenzyme Q10 | 华北制药股份有限公司 | 2020-11-27 | — | — | CN | claimed |
| CN-111440563-A | Curing agent and urea-formaldehyde resin composition containing same | 杭州临安迪恩化工有限公司 | 2020-07-24 | — | — | CN | claimed |
| CN-110963923-A | Method for preparing 1, 5-pentanediamine by one-step chemical decarboxylation of L-lysine | 郑州中科新兴产业技术研究院 | 2020-04-07 | — | — | CN | claimed |
| CN-110846302-A | Lysine decarboxylase curing method and application thereof | 上海凯赛生物技术股份有限公司 | 2020-02-28 | — | — | CN | claimed |
| CN-107779447-A | Immobilised lysine decarboxylase, its preparation, 1,5 pentanediamine preparation methods and product | 上海凯赛生物技术研发中心有限公司 | 2018-03-09 | — | — | CN | claimed |
| CN-107779446-A | Immobilised lysine decarboxylase, its preparation, 1,5 pentanediamine preparation methods and product | 上海凯赛生物技术研发中心有限公司 | 2018-03-09 | — | — | CN | claimed |
| EP-0491638-A2 | Method of making granulated L-lysine | ARCHER-DANIELS-MIDLAND COMPANY (US) | 1992-06-24 | — | — | EP | claimed |
| US-4686211-A | Medical composition for external application | KAO CORPORATION (JP) | 1987-08-11 | — | — | US | claimed |
| US-3932608-A | 1A, 2A-AMINO ACID PHOSPHATES, CARIOSTATIC AGENTS | GENERAL MILLS, INC. (US) | 1976-01-13 | — | — | US | claimed |