Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.80 |
| ▸ | ARG2 | P78540 | 4/20 | 0.50 |
| ▸ | ARG1 | P05089 | 3/20 | 0.50 |
| ▸ | OTC | P00480 | 1/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | GLUL | P15104 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL103555 | 0.98 | GSR (0.83) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL1825922 | 0.98 | GSR (0.83) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL1446119 | 0.98 | GSR (0.83) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL11803679 | 0.98 | GSR (0.83) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL27494339 | 0.96 | GSR (0.74) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL11671036 | 0.96 | GSR (0.80) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL11670724 | 0.96 | GSR (0.80) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL11801574 | 0.96 | GSR (0.80) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL11798743 | 0.96 | GSR (0.80) | GSRARG2ARG1OTCRNPEP | |
| Lysine SCHEMBL5444480 | 0.96 | GSR (0.80) | GSRARG2ARG1OTCRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022581-A | ANIMAL FEED ADDITIVE COMPOSITION; POWDERY OR GRANULATE RUMINANT FEED ADDITIVE COMPOSITION WHICH IS STABLE IN A RUMEN OF A RUMINANT AND RELEASES LYSINE IN LOWER DIGESTIVE ORGAN | AJINOMOTO CO., INC. (JP) | 2000-02-08 | — | — | US | claimed |
| EP-0826662-A1 | Aggregate crystals of phosphoric acid/lysine/magnesium composite salt and process for producing the same | Ajinomoto Co., Inc. (JP) | 1998-03-04 | — | — | EP | claimed |
| US-6022581-A | ANIMAL FEED ADDITIVE COMPOSITION; POWDERY OR GRANULATE RUMINANT FEED ADDITIVE COMPOSITION WHICH IS STABLE IN A RUMEN OF A RUMINANT AND RELEASES LYSINE IN LOWER DIGESTIVE ORGAN | AJINOMOTO CO., INC. (JP) | 2000-02-08 | — | — | US | disclosed |
| US-6022581-A | ANIMAL FEED ADDITIVE COMPOSITION; POWDERY OR GRANULATE RUMINANT FEED ADDITIVE COMPOSITION WHICH IS STABLE IN A RUMEN OF A RUMINANT AND RELEASES LYSINE IN LOWER DIGESTIVE ORGAN | AJINOMOTO CO., INC. (JP) | 2000-02-08 | — | — | US | disclosed |
| US-6022581-A | ANIMAL FEED ADDITIVE COMPOSITION; POWDERY OR GRANULATE RUMINANT FEED ADDITIVE COMPOSITION WHICH IS STABLE IN A RUMEN OF A RUMINANT AND RELEASES LYSINE IN LOWER DIGESTIVE ORGAN | AJINOMOTO CO., INC. (JP) | 2000-02-08 | — | — | US | disclosed |
| CN-1179900-A | Aggregate crystals of phosphoric acid/lysine/magnesium composite salt and process for producing the same | AJINOMOTO KK (JP) | 1998-04-29 | — | — | CN | disclosed |
| CN-1179900-A | Aggregate crystals of phosphoric acid/lysine/magnesium composite salt and process for producing the same | AJINOMOTO KK (JP) | 1998-04-29 | — | — | CN | disclosed |
| EP-0826662-A1 | Aggregate crystals of phosphoric acid/lysine/magnesium composite salt and process for producing the same | Ajinomoto Co., Inc. (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0826662-A1 | Aggregate crystals of phosphoric acid/lysine/magnesium composite salt and process for producing the same | Ajinomoto Co., Inc. (JP) | 1998-03-04 | — | — | EP | disclosed |
| EP-0826662-A1 | Aggregate crystals of phosphoric acid/lysine/magnesium composite salt and process for producing the same | Ajinomoto Co., Inc. (JP) | 1998-03-04 | — | — | EP | disclosed |