Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.72 |
| ▸ | DRD3 | P35462 | 2/20 | 0.72 |
| ▸ | DRD4 | P21917 | 1/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355543 | 1.00 | DRD2 (0.72) | DRD2DRD3DRD4ABCG2 | |
| SCHEMBL19219858 | 0.91 | DRD2 (0.85) | DRD2DRD3DRD4 | |
| SCHEMBL10355397 | 0.90 | DRD2 (0.81) | DRD2DRD3ABCG2 | |
| SCHEMBL10355398 | 0.90 | DRD2 (0.81) | DRD2DRD3ABCG2 | |
| SCHEMBL28530726 | 0.88 | DRD3 (0.63) | DRD2DRD3DRD4ABCG2 | |
| SCHEMBL28546528 | 0.87 | DRD3 (0.62) | DRD2DRD3DRD4ABCG2 | |
| SCHEMBL28541227 | 0.87 | DRD3 (0.62) | DRD2DRD3DRD4ABCG2 | |
| SCHEMBL10355427 | 0.85 | DRD2 (0.80) | DRD2DRD3ABCG2 | |
| SCHEMBL10355426 | 0.85 | DRD2 (0.80) | DRD2DRD3ABCG2 | |
| SCHEMBL28538960 | 0.84 | DRD3 (0.68) | DRD2DRD3ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207913-B1 | CATECHOL CARBOXAMIDES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES AND A PHARMACEUTICAL PREPARATION | Astra Läkemedel Aktiebolag (SE) | 1990-10-31 | — | — | EP | disclosed |