Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.81 |
| ▸ | DRD3 | P35462 | 1/20 | 0.77 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355398 | 1.00 | DRD2 (0.81) | DRD2DRD3ABCG2 | |
| SCHEMBL10355543 | 0.90 | DRD2 (0.72) | DRD2DRD3ABCG2 | |
| SCHEMBL10355545 | 0.90 | DRD2 (0.72) | DRD2DRD3ABCG2 | |
| SCHEMBL10355427 | 0.88 | DRD2 (0.80) | DRD2DRD3ABCG2 | |
| SCHEMBL10355426 | 0.88 | DRD2 (0.80) | DRD2DRD3ABCG2 | |
| SCHEMBL10355469 | 0.87 | DRD3 (1.00) | DRD2DRD3ABCG2 | |
| Epidepride SCHEMBL8961795 | 0.87 | DRD2 (0.81) | DRD2DRD3ABCG2 | |
| Epidepride SCHEMBL29521228 | 0.87 | DRD2 (0.81) | DRD2DRD3ABCG2 | |
| Epidepride SCHEMBL8961800 | 0.87 | DRD2 (0.81) | DRD2DRD3ABCG2 | |
| SCHEMBL10355399 | 0.87 | DRD2 (0.81) | DRD2DRD3ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207913-B1 | CATECHOL CARBOXAMIDES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES AND A PHARMACEUTICAL PREPARATION | Astra Läkemedel Aktiebolag (SE) | 1990-10-31 | — | — | EP | disclosed |
| WO-1986007591-A1 | CATECHOLCARBOXAMIDES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES AND A PHARMACEUTICAL PREPARATION | Astra Läkemedel Aktiebolag (SE) | 1986-12-31 | — | — | WO | disclosed |