Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10355648 | 1.00 | KMT2A (0.41) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL10347580 | 0.82 | KMT2A (0.39) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL10355464 | 0.82 | MAPT (0.40) | KMT2ASMN1; SMN2MEN1MAPK1HPGD | |
| SCHEMBL10355463 | 0.82 | MAPT (0.40) | KMT2ASMN1; SMN2MEN1MAPK1HPGD | |
| SCHEMBL10875327 | 0.82 | NR5A1 (0.41) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL7796911 | 0.81 | CYP2C9 (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL7796912 | 0.81 | CYP2C9 (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL10347161 | 0.81 | KMT2A (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL10347164 | 0.81 | KMT2A (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1 | |
| SCHEMBL10355659 | 0.81 | HSD17B3 (0.42) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194153-B1 | PYRIDINE DERIVATIVES | Chisso Corporation (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4684477-A | LOW VISCOSITY, LOW VOLTAGE | CHISSO CORPORATION (JP) | 1987-08-04 | — | — | US | disclosed |
| EP-0194153-A2 | Pyridine derivatives | Chisso Corporation (JP) | 1986-09-10 | — | — | EP | disclosed |