Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 7/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.49 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603708 | 1.00 | HTT (0.58) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9717543 | 0.93 | HTT (0.53) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22500510 | 0.87 | HTT (0.58) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7300776 | 0.86 | TSHR (0.52) | HTTALDH1A1THRBTHRAHSD17B3 | |
| SCHEMBL7430789 | 0.84 | HTT (0.54) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL22500456 | 0.82 | HTT (0.51) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9838543 | 0.81 | HTT (0.51) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10351740 | 0.80 | HTT (0.61) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10350952 | 0.80 | HTT (0.61) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10794438 | 0.80 | HTT (0.61) | HTTMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251139-B1 | CHEMILUMINESCENT COMPOSITION, AND A REACTIVE COMPONENT SUITABLE FOR SUCH A COMPOSITION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-09-26 | — | — | EP | disclosed |
| EP-0251139-A2 | Chemiluminescent composition, and a reactive component suitable for such a composition | FARMITALIA CARLO ERBA S.r.l. (IT) | 1988-01-07 | — | — | EP | disclosed |