Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.53 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 5/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603708 | 0.84 | HTT (0.58) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL10356111 | 0.84 | HTT (0.58) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL9717543 | 0.77 | HTT (0.53) | HTTMEN1KMT2APAK1ALDH1A1 | |
| SCHEMBL11295651 | 0.76 | HTT (0.56) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL11079724 | 0.75 | HTT (0.59) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL28688851 | 0.75 | HTT (0.59) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL11301129 | 0.75 | HTT (0.59) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL11075491 | 0.74 | PLA2G2A (0.57) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL22500510 | 0.74 | HTT (0.58) | HTTPLA2G2APLA2G5FFAR1MEN1 | |
| SCHEMBL19296351 | 0.74 | PLA2G2A (0.57) | HTTPLA2G2APLA2G5FFAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095295-B1 | CYCLIC PEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-01-14 | — | — | EP | disclosed |
| US-4537717-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0095295-A1 | Cyclic peptide derivatives | ELI LILLY AND COMPANY (US) | 1983-11-30 | — | — | EP | disclosed |