SCHEMBL10356145

SCHEMBL10356145

Cc1ccc(Sc2cccc3c2C(=O)c2c(N)ccc(N)c2C3=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.56
MAPK1 P28482 4/20 0.56
KDM4E B2RXH2 2/20 0.56
NSD2 O96028 1/20 0.56
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
L3MBTL1 Q9Y468 4/20 0.46
TDP1 Q9NUW8 3/20 0.46
NPSR1 Q6W5P4 2/20 0.46
HKDC1 Q2TB90 2/20 0.46
ADORA2A P29274 6/20 0.46
CSNK1A1 P48729 2/20 0.46
CSNK1D P48730 2/20 0.46
CSNK1G1 Q9HCP0 2/20 0.46
MAOA P21397 2/20 0.46
FGR P09769 1/20 0.46
PIM1 P11309 1/20 0.46
DYRK1A Q13627 1/20 0.46
HIPK2 Q9H2X6 1/20 0.46
P4HB P07237 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11580274 0.94 MAPT (0.55) MAPTMAPK1KDM4ENSD2MEN1
SCHEMBL10355983 0.92 MEN1 (0.54) MAPTMAPK1KDM4ENSD2MEN1
SCHEMBL4485448 0.89 MAPT (0.64) MAPTMAPK1KDM4ENSD2MEN1
SCHEMBL5187613 0.85 MAPT (0.68) MAPTMAPK1KDM4ENSD2MEN1
SCHEMBL14207786 0.85 MAPT (0.73) MAPTMAPK1KDM4ENSD2MEN1
SCHEMBL10355976 0.83 MAPT (0.54) MAPTMAPK1KDM4ENSD2MEN1
SCHEMBL10355833 0.82 MAPT (0.60) MAPTMAPK1KDM4ENSD2MEN1
SCHEMBL13797721 0.81 MAPT (0.54) MAPTMAPK1KDM4ENSD2MEN1
SCHEMBL11579534 0.80 MAPT (0.75) MAPTMAPK1KDM4ENSD2MEN1
SCHEMBL6365480 0.80 MAPK1 (0.64) MAPTMAPK1KDM4ENSD2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0103095-B1 DICHROIC MATERIAL CONTAINING ANTHRAQUINONE DYES BAYER AG (DE) 1990-08-29 EP disclosed
EP-0103095-A2 Dichroic material containing anthraquinone dyes BAYER AG (DE) 1984-03-21 EP disclosed