Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | FGR | P09769 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356145 | 0.94 | MAPT (0.56) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL4485448 | 0.92 | MAPT (0.64) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL14207786 | 0.88 | MAPT (0.73) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL5187613 | 0.88 | MAPT (0.68) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL10355983 | 0.87 | MEN1 (0.54) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL11579534 | 0.86 | MAPT (0.75) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL11583208 | 0.85 | KDM4E (0.55) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL13797721 | 0.84 | MAPT (0.54) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL6365480 | 0.82 | MAPK1 (0.64) | MAPTMAPK1KDM4ENSD2ADORA2A | |
| SCHEMBL11581942 | 0.81 | MAPT (0.84) | MAPTMAPK1KDM4ENSD2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126626-A | DYES, POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |