Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | F9 | P00740 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356154 | 0.86 | TSHR (0.49) | ALDH1A1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL10784895 | 0.82 | MAPT (0.48) | ALDH1A1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL11085561 | 0.77 | SCN5A (0.46) | SMN1; SMN2RAB9ANPSR1LMNATSHR | |
| SCHEMBL11082614 | 0.74 | SCN5A (0.33) | SMN1; SMN2RAB9ANPSR1LMNATSHR | |
| SCHEMBL7898197 | 0.74 | USP2 (0.56) | ALDH1A1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL10785944 | 0.73 | CHRM3 (0.41) | ALDH1A1NPSR1MAPK1TSHRTDP1 | |
| SCHEMBL2170548 | 0.73 | USP2 (0.55) | ALDH1A1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL2010417 | 0.72 | USP2 (0.67) | ALDH1A1SMN1; SMN2NPC1HPGDRAB9A | |
| SCHEMBL6463823 | 0.71 | PPARA (0.59) | SMN1; SMN2NPC1HPGDRAB9ANPSR1 | |
| SCHEMBL2011265 | 0.71 | USP2 (0.58) | ALDH1A1SMN1; SMN2NPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116787-B1 | 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-03-18 | — | — | EP | claimed |
| EP-0116787-A1 | 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-29 | — | — | EP | claimed |
| EP-0179662-B1 | FODDER ADDITIVE AND A PROCESS FOR THE PREPARATION THEREOF | RICHTER GEDEON VEGYESZET (HU) | 1990-10-03 | — | — | EP | disclosed |
| US-4659712-A | ELIMINATION OF METABOLITES FROM LIVER | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1987-04-21 | — | — | US | disclosed |
| EP-0116787-B1 | 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-03-18 | — | — | EP | disclosed |
| CN-85107783-A | Feed additive and preparation method thereof | — | 1986-08-27 | — | — | CN | disclosed |
| US-4605785-A | I(DUCE POLYSUBSTRATE MONOOXYGENASE ENZYME SYSTEM OF LIV)R WI HOUT GENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-08-12 | — | — | US | disclosed |
| EP-0179662-A2 | Fodder additive and a process for the preparation thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-30 | — | — | EP | disclosed |
| EP-0116787-A1 | 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-29 | — | — | EP | disclosed |