Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356151 | 0.86 | ALDH1A1 (0.45) | TSHRLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10783526 | 0.82 | NPC1 (0.50) | TSHRNPC1RAB9ATRPM8 | |
| SCHEMBL10785722 | 0.77 | BCHE (0.47) | TSHRLMNANPC1RAB9AHPGD | |
| SCHEMBL11085561 | 0.76 | SCN5A (0.46) | TSHRLMNARAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL11082614 | 0.73 | SCN5A (0.33) | TSHRLMNARAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL10785944 | 0.72 | CHRM3 (0.41) | TSHRALDH1A1MAPK1NPSR1 | |
| SCHEMBL10787948 | 0.70 | NPC1 (0.54) | TSHRNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL11618396 | 0.70 | KIF11 (0.49) | SMN1; SMN2KMT2AMEN1MAPK1NPSR1 | |
| SCHEMBL10356364 | 0.69 | TRPM8 (0.55) | TSHRNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL10784895 | 0.68 | MAPT (0.48) | LMNANPC1RAB9ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116787-B1 | 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-03-18 | — | — | EP | claimed |
| EP-0116787-A1 | 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-29 | — | — | EP | claimed |
| EP-0179662-B1 | FODDER ADDITIVE AND A PROCESS FOR THE PREPARATION THEREOF | RICHTER GEDEON VEGYESZET (HU) | 1990-10-03 | — | — | EP | disclosed |
| US-4659712-A | ELIMINATION OF METABOLITES FROM LIVER | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1987-04-21 | — | — | US | disclosed |
| EP-0116787-B1 | 1,1-DIPHENYLPROPANOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1987-03-18 | — | — | EP | disclosed |
| US-4605785-A | I(DUCE POLYSUBSTRATE MONOOXYGENASE ENZYME SYSTEM OF LIV)R WI HOUT GENTS | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1986-08-12 | — | — | US | disclosed |
| EP-0179662-A2 | Fodder additive and a process for the preparation thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1986-04-30 | — | — | EP | disclosed |
| EP-0116787-A1 | 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-29 | — | — | EP | disclosed |