Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.46 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356151 | 0.77 | ALDH1A1 (0.45) | LMNATSHRRAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL10356154 | 0.76 | TSHR (0.49) | LMNATSHRRAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL10785944 | 0.74 | CHRM3 (0.41) | SCN5ASCN9AKIF11KCNH2CHRM3 | |
| SCHEMBL11082614 | 0.73 | SCN5A (0.33) | SCN5ASCN9AKIF11CCR6KCNH2 | |
| SCHEMBL11618396 | 0.72 | KIF11 (0.49) | SCN5ASCN9AKIF11KCNH2CHRM3 | |
| SCHEMBL10787907 | 0.68 | MAOB (0.44) | POLB | |
| SCHEMBL7942001 | 0.67 | ATM (0.40) | KCNH2LMNASMN1; SMN2 | |
| SCHEMBL10356950 | 0.67 | TSHR (0.41) | SCN5ASCN9AKIF11CHRM3TSHR | |
| SCHEMBL11619787 | 0.66 | SMN1; SMN2 (0.46) | KCNH2LMNATSHRSMN1; SMN2NPSR1 | |
| SCHEMBL10789110 | 0.66 | SCN5A (0.45) | SCN5ASCN9AKIF11CHRM3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116787-A1 | 1,1-Diphenylpropanol derivatives, process for their preparation and pharmaceutical compositions containing them | Richter Gedeon Vegyészeti Gyár R.T. (HU) | 1984-08-29 | — | — | EP | disclosed |