Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2360694 | 0.86 | ESR1 (0.54) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL2738485 | 0.84 | LMNA (0.67) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL12164090 | 0.84 | LMNA (0.67) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL5024803 | 0.84 | LMNA (0.67) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL6570384 | 0.83 | LMNA (0.40) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL6570381 | 0.83 | LMNA (0.40) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL11862021 | 0.82 | LMNA (0.72) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL11857394 | 0.82 | LMNA (0.72) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL11857389 | 0.82 | LMNA (0.72) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL4623091 | 0.82 | LMNA (0.72) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285548-B1 | PROCESS FOR THE PREPARATION OF 17-ALPHA-ETHYNYL-17-BETA-HYDROXY-18-METHYL-4,15-ESTRADIEN-3-ONE, AND INTERMEDIATES FOR THIS PROCESS | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-09-05 | — | — | EP | claimed |
| EP-0285548-A1 | Process for the preparation of 17-alpha-ethynyl-17-beta-hydroxy-18-methyl-4,15-estradien-3-one, and intermediates for this process | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-10-05 | — | — | EP | claimed |
| EP-0285548-B1 | PROCESS FOR THE PREPARATION OF 17-ALPHA-ETHYNYL-17-BETA-HYDROXY-18-METHYL-4,15-ESTRADIEN-3-ONE, AND INTERMEDIATES FOR THIS PROCESS | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-09-05 | — | — | EP | disclosed |
| US-4923640-A | Process for the production of 17α-ethinyl-17β-hydroxy-18-methyl-4,15-estradien-3-one and new intermediate products for this process | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-05-08 | — | — | US | disclosed |
| EP-0285548-A1 | Process for the preparation of 17-alpha-ethynyl-17-beta-hydroxy-18-methyl-4,15-estradien-3-one, and intermediates for this process | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-10-05 | — | — | EP | disclosed |