SCHEMBL10356285

SCHEMBL10356285

Cc1c(C)c(C(=O)c2ccc(C(=O)O)c(C(=O)O)c2)c(C)c(C)c1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.54
CDC25A P30304 1/20 0.54
CDC25B P30305 1/20 0.54
POLB P06746 4/20 0.53
TDP1 Q9NUW8 4/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
GFER P55789 1/20 0.46
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 3/20 0.45
AKR1C3 P42330 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MYC P01106 2/20 0.39
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7767090 0.83 HSD17B10 (0.58) HSD17B10CDC25ACDC25BPOLBTDP1
SCHEMBL10492132 0.81 TSHR (0.45) L3MBTL1GFERALDH1A1
SCHEMBL8906541 0.79 HSD17B10 (0.58) HSD17B10CDC25ACDC25BPOLBTDP1
SCHEMBL26963255 0.78 CDC25B (0.66) HSD17B10CDC25ACDC25BPOLBTDP1
SCHEMBL29404709 0.78 POLB (0.80) HSD17B10CDC25ACDC25BPOLBTDP1
SCHEMBL48886 0.78 POLB (0.80) HSD17B10CDC25ACDC25BPOLBTDP1
SCHEMBL1538420 0.77 POLB (0.67) HSD17B10CDC25ACDC25BPOLBTDP1
SCHEMBL7771248 0.76 HSD17B10 (0.62) HSD17B10CDC25ACDC25BPOLBTDP1
SCHEMBL7772657 0.76 CDC25A (0.58) HSD17B10CDC25ACDC25BPOLBTDP1
SCHEMBL7045921 0.76 TDP1 (0.84) HSD17B10CDC25ACDC25BPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0182745-B1 POLYIMIDES, PROCESS FOR THEIR FABRICATION, AND THEIR USE CIBA-GEIGY AG (CH) 1990-11-22 EP disclosed
US-4808732-A CHEMICAL INTERMEDIATES FOR HOMO AND COPOLYIMIDES CIBA-GEIGY CORPORATION (US) 1989-02-28 US disclosed
US-4629685-A PROTECTIVE FILMS OR PHOTOGRAPHIC RELIEF IMAGES CIBA-GEIGY CORPORATION (US) 1986-12-16 US disclosed
EP-0182745-A2 Polyimides, process for their fabrication, and their use CIBA-GEIGY AG (CH) 1986-05-28 EP disclosed