SCHEMBL10492132

SCHEMBL10492132

CCCCNC(=O)c1cc(C(=O)c2c(C)c(C)c(N)c(C)c2C)ccc1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.45
HTT P42858 1/20 0.45
ALOX15 P16050 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
BCL2 P10415 1/20 0.42
MCL1 Q07820 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
HPGD P15428 1/20 0.40
GFER P55789 1/20 0.40
HTR2A P28223 1/20 0.39
NAAA Q02083 2/20 0.39
LMNA P02545 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10492123 0.88 TSHR (0.47) TSHRHTTALOX15SMN1; SMN2BCL2
SCHEMBL8648125 0.86 TSHR (0.55) TSHRHTTALOX15SMN1; SMN2BCL2
Hydrochloric Acid SCHEMBL8646484 0.85 TSHR (0.54) TSHRHTTALOX15SMN1; SMN2BCL2
SCHEMBL10492148 0.84 POLB (0.43) TSHRHTTSMN1; SMN2BCL2MCL1
SCHEMBL10356285 0.81 HSD17B10 (0.54) L3MBTL1GFERALDH1A1
SCHEMBL17361212 0.80 NAAA (0.55) TSHRHTTALOX15SMN1; SMN2L3MBTL1
SCHEMBL17361214 0.78 NAAA (0.55) TSHRHTTALOX15SMN1; SMN2L3MBTL1
SCHEMBL3754605 0.77 NAAA (0.57) TSHRHTTALOX15SMN1; SMN2L3MBTL1
SCHEMBL10440167 0.77 NAAA (0.57) TSHRHTTALOX15SMN1; SMN2L3MBTL1
SCHEMBL22268780 0.77 TSHR (0.61) TSHRHTTALOX15SMN1; SMN2BCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4808732-A CHEMICAL INTERMEDIATES FOR HOMO AND COPOLYIMIDES CIBA-GEIGY CORPORATION (US) 1989-02-28 US disclosed
US-4677186-A AMINO DICARBOXYLIC ACID MONOMERS, PROTECITVE COATINGS CIBA-GEIGY CORPORATION (US) 1987-06-30 US disclosed
US-4629685-A PROTECTIVE FILMS OR PHOTOGRAPHIC RELIEF IMAGES CIBA-GEIGY CORPORATION (US) 1986-12-16 US disclosed