Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10559088 | 1.00 | SLC6A4 (0.64) | SLC6A4SLC6A3SLC6A2MEN1ALDH1A1 | |
| SCHEMBL10356635 | 1.00 | SLC6A4 (0.64) | SLC6A4SLC6A3SLC6A2MEN1ALDH1A1 | |
| SCHEMBL10356309 | 1.00 | SLC6A4 (0.64) | SLC6A4SLC6A3SLC6A2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10356877 | 0.99 | SLC6A4 (0.65) | SLC6A4SLC6A3SLC6A2MEN1ALDH1A1 | |
| SCHEMBL10554280 | 0.95 | ACHE (0.64) | SLC6A4SLC6A3SLC6A2MEN1ALDH1A1 | |
| SCHEMBL10356303 | 0.92 | SLC6A4 (0.70) | SLC6A4SLC6A3SLC6A2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10552395 | 0.91 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2MEN1ALDH1A1 | |
| SCHEMBL10552245 | 0.89 | SLC6A4 (0.78) | SLC6A4SLC6A3SLC6A2MEN1ALDH1A1 | |
| SCHEMBL10550540 | 0.89 | SLC6A4 (0.78) | SLC6A4SLC6A3SLC6A2MEN1ALDH1A1 | |
| SCHEMBL10357008 | 0.89 | SLC6A3 (0.56) | SLC6A4SLC6A3SLC6A2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243905-B1 | 1-(omega-[bis-(phenyl)alkoxy]-alkyl)-4-(di-(phenyl)-methyl)piperazines, process for their preparation and medicines containing them | RICHTER GEDEON VEGYESZET (HU) | 1990-10-10 | — | — | EP | claimed |
| US-4868184-A | DISEASES ARISING FROM LOW DOPAMINE LEVEL; ANTIDEPRESSANTS; PARKINSON'S DISEASE; NERVOUS SYSTEM, GLANDULAR AND UROGENITAL SYSTEM DISORDERS | RICHTER GEDEON VEGYESZETI GYAR (HU) | 1989-09-19 | — | — | US | claimed |
| EP-0243905-B1 | 1-(omega-[bis-(phenyl)alkoxy]-alkyl)-4-(di-(phenyl)-methyl)piperazines, process for their preparation and medicines containing them | RICHTER GEDEON VEGYESZET (HU) | 1990-10-10 | — | — | EP | disclosed |
| US-4868184-A | DISEASES ARISING FROM LOW DOPAMINE LEVEL; ANTIDEPRESSANTS; PARKINSON'S DISEASE; NERVOUS SYSTEM, GLANDULAR AND UROGENITAL SYSTEM DISORDERS | RICHTER GEDEON VEGYESZETI GYAR (HU) | 1989-09-19 | — | — | US | disclosed |