Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.64 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.64 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | PRKACA | P17612 | 1/20 | 0.59 |
| ▸ | FLT1 | P17948 | 1/20 | 0.59 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.59 |
| ▸ | CDK2 | P24941 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | AKT1 | P31749 | 1/20 | 0.59 |
| ▸ | FLT4 | P35916 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356572 | 1.00 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL10357148 | 1.00 | ALDH1A1 (0.69) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL17369057 | 0.84 | ALDH1A1 (0.73) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL1101522 | 0.84 | ALDH1A1 (0.77) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL751213 | 0.84 | ALDH1A1 (0.77) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL5968858 | 0.84 | ALDH1A1 (0.77) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL13229317 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL28619644 | 0.83 | KMT2A (0.60) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL28617369 | 0.83 | KMT2A (0.60) | ALDH1A1KMT2AMEN1LMNANPC1 | |
| SCHEMBL28630813 | 0.83 | KMT2A (0.60) | ALDH1A1KMT2AMEN1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213924-B1 | P-ACYLAMINOBENZAMIDES | ELI LILLY AND COMPANY (US) | 1990-10-17 | — | — | EP | disclosed |
| EP-0213924-A2 | p-Acylaminobenzamides | ELI LILLY AND COMPANY (US) | 1987-03-11 | — | — | EP | disclosed |
| US-4642379-A | 4-ACYLAMINO BENZAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-02-10 | — | — | US | disclosed |