Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | TGM2 | P21980 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.54 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | PRKACA | P17612 | 1/20 | 0.54 |
| ▸ | FLT1 | P17948 | 1/20 | 0.54 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | FLT4 | P35916 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28630813 | 1.00 | KMT2A (0.60) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL28617369 | 1.00 | KMT2A (0.60) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL28620280 | 0.87 | TGM2 (0.61) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL28617460 | 0.87 | HDAC1 (0.63) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL28615912 | 0.87 | TGM2 (0.61) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL28627367 | 0.87 | TGM2 (0.47) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL28619301 | 0.87 | TGM2 (0.61) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL28624100 | 0.87 | B3GNT2 (0.47) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL28619303 | 0.85 | MAPK1 (0.48) | KMT2AMEN1ALDH1A1LMNANPC1 | |
| SCHEMBL28620836 | 0.85 | MAPK1 (0.48) | KMT2AMEN1ALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438279-B | Small molecule compound for overcoming EGFR drug-resistant mutation and preparation method and application thereof | 四川大学 | 2021-08-31 | — | — | CN | disclosed |